Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Electrophile detoxification"”.
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Structural and functional elucidation of four putative PQS-binding proteins in Pseudomonas aeruginosa
… in this study suggested a possible role in electrophile detoxification, a hypothesis which I confirmed *in vitro* using 1D NMR. To complement the novel PfpI structural and biochemical data, I generated and confirmed “clean” *pfpI* deletion mutants for phenotypic and ‘omic analyses. I …
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THE ROLE OF NRF2 IN PREVENTING OXIDATIVE/ELECTROPHILIC STRESS-INDUCED LIVER INJURY
… The results indicate that Nrf2 facilitates electrophile detoxification through inducing non P-450 phase-I enzymes that reduce electrophiles, Gsts that conjugate electrophiles, and efflux transporters that excrete electrophile-GSH conjugates out of cells. In addition to the assessment of the …