Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Electrodiffusion"”.
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Modeling Regional Variation of Cortical Spreading Depression: A Computational Study
… this thesis we present a multi-phasic continuum electrodiffusion model of spreading depression. The main result of this work is the efficient numerical simulation of 2D and 3D versions of this model. We make use of these simulations by focusing on the introduction of NMDA receptors and their …
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Investigating the effects of impermeant anions on the electrical and computational properties on neurons
… is poorly understood. Using a multicompartment electrodiffusion-based computational model I investigated the influence of impermeant anions on neuronal cellular physiology, passive cable properties, and synaptic integration. Spatial differences in the average charge of impermeant anions result …
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Steady-State Poisson-Nernst-Planck Systems: Asymptotic expansions and applications to ion channels
… a steady state Poisson-Nernst-Plank system for electrodiffusion. The solution to the PNP system gives a relation between the current and electric potential of the ions in the channel, called the I-V curve. In this thesis, we will discuss the matched asymptotic expansions method of solving a …
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Exploring the determinants of chloride homeostasis in neurons using biophysical models
… ion conductances, impermeant anions, electrodiffusion, water fluxes and cation-chloride cotransporters (CCCs) play roles in setting the Cl- driving force. Importantly, I show that while impermeant anions can contribute to setting [Cl- ]i in neurons, they have a negligible effect on the …
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Computational analyses on the structure-function relation in ion channels
… protein channels. The algorithm - based on the electrodiffusion theory - is computational inexpensive, and was used for an extensive analysis on the molecular determinants of the channel conductance. The first record of ion-fluxes through a single protein channel dates back to 1976, and since …
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Characterisation of imperfections in single crystals of high purity synthetic quartz
… a study of quartz which had been treated by electrodiffusion, or sweeping. Crystal lattice strain and sweeping damage was studied using double crystal topography at the Synchrotron Radiation Source, (SRS), at the Daresbury Laboratory. Metal ion impurities were shown to incorporate …
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Analysis of a Partial Differential Equation Model of Surface Electromigration
<p>A Partial Differential Equation (PDE) based model combining surface electromigration and wetting is developed for the analysis of the morphological instability of mono-crystalline metal films in a high temperature environment typical to operational conditions of microelectronic interconnects. …