Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 71 for “"Electrochemical detection"”.
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Electrochemical detection of chemical warfare agents
tert-butyl 1’-methoxycarbonyl-1-ferrocenecarbamate, Boc-NH-Fc-COOMe, (1) was synthesized according to the literature procedure and modified to 1-amino-n′-ferrocenemethylcarboxylate, 1,n′-H₂N-Fc-COOCH₃ (2) by removing the Boc-group with TFA/Et₃N mixture in dichloromethane. Compound 2 reacted with …
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Development of electrochemical detection for capillary electrophoreses
… this work was to develop reliable and sensitive electrochemical (EC) detection for capillary electrophoresis. To achieve this goal, electrochemical behavior of the electrolyte and analytes and the factors affecting the behavior were studied by on-line cyclic voltammetry (CV) to understand …
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Enzyme-Linked Electrochemical Detection of Urinary Sarcosine
… diagnostics are crucial for the early detection of prostate cancer (PCa). One such biomarker that may be useful in PCa diagnostics is urinary sarcosine (N-methylglycine). However, its utility is confounded by several factors: the small differences in metabolite concentration that …
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Sensitive Electrochemical Detection Platforms for Anthracene and Pyrene
Der elektrochemische Nachweis von polycyclischen aromatischen Kohlenwasserstoffen (PAK), zu denen Anthracen und Pyren gehören, bietet eine kostengünstigere, einfachere und schnellere alternative Analysemethode als herkömmliche Methoden wie GC und HPLC. Im Vergleich zu diesen Methoden weist er …
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Electrochemical detection of interactions between DNA and various ligands
… diseases. Because of the great sensitivity of electrochemical techniques and their potential utility in characterizing interactions between macromolecules, electrochemistry has great potential as a diagnostic tool for any disease involving antibodies. Anti-DNA antibodies are present in many …
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Electrochemical Detection of Aliphatic Sulfur Compounds in Liquid Coal Extracts
… were studied using reverse phase HPLC with electrochemical detection in a acetonitrile/water mobile phase. Coal samples IBC 101 and IBC 105 were extracted with THF and hexane. The liquid coal extracts were fractionated using a simple chromatographic technique. The fractionated extracts were …
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Maximization of the Electrochemical Detection of Orthophosphate in Organic-Aqueous Solutions.
It is well known that phosphorus is an essential nutrient for the growth of organisms. Therefore, it plays an important role as a growth-limiting nutrient in natural waters. Phosphorus-stimulated proliferation of plant micro- and macroorganisms in natural waters accelerates eutrophication thereby …
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The Biomedical Application of Conducting Polymers for the Electrochemical Detection of Diseases
… can be used as biosensing devices for the detection and monitoring of illnesses. The major advantage they provide is in the potential to function as portable, rapid, inexpensive biosensors when compared to what is currently available. In this work, an electrochemical biosensor for the …
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Carbon Paste Macrocycle Doped Composite Electrodes for the Selective Electrochemical Detection of Dopamine
… electrodes modified with macrocycles for the electrochemical detection of DA is reported. The different macrocycles employed were based on cyclodextrin derivatives and consist of sulfated β-CD (S-β-CD), carboxymethyl β-CD (CM-β-CD), Ferrocene complex β-CD (Fc-β-CD), Heptakis …
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Electrochemical Detection of Anti-Biofilm Activity Using Unnatural Amino Acid-Containing Antimicrobial Peptides
… the costs associated with it and the reagents. Electrochemical biosensors can remedy some of those drawbacks by offering speed and cost benefits. Electrochemical biosensors consisting of Layer-by-Layer (LbL) modified electrodes were constructed. These sensors were fabricated to test the …
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Measurement of Ascorbic Acid and Dehydroascorbic Acid in Mammalian Tissues using HPLC with Electrochemical Detection
… compounds making their measurement difficult. Detection of small amounts of AA and dehydroascorbic acid (DHAA) is essential for determining the biochemical function of the vitamin in cells and subcellular organelles. While a variety of techniques exist which detect millimolar levels of AA, …
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Oxidative stress markers in neurological diseases and disorders: electrochemical detection of hydrogen peroxide and nitric oxide
… aim of this thesis is to further demonstrate the electrochemical detection of nitric oxide (NO) and hydrogen peroxide (H2O2) in-vitro, to advance the previously demonstrated detection of brain NO and to demonstrate the novel in-vivo detection of H2O2 using a paired catalase-based biosensor. We …
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Esterase 2-oligodeoxynucleotide conjugates as enzyme reporter for electrochemical detection of DNA and identification of bacterial species
… To improve its application of nucleic acids detection, a suitable enzyme reporter is expected. Esterase 2 (EST2) from Alicyclobacillus acidocaldarius was introduced and mutated to have an accessible cysteine residue at 118th codon. This esterase was purified by a single-step affinity …
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Rapid separation of phenolic flavourings by liquid chromatography and nanomolar electrochemical detection at a boron-doped diamond electrode
… and anti-microbial. Their investigation and detection in plants, food and beverages require the development of rapid, selective and sensitive analytical methods. In this thesis, an overview of plant secondary metabolites, their classification and physiological properties are given. The …
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Development of stationary phase materials and methods for analysis of pharmaceuticals via high-performance liquid chromatography and electrochemical detection
… analysis via liquid chromatography (LC) and electrochemical analysis at a boron-doped diamond (BDD) electrode this research explores and characterises a novel polymer immobilised porous silica particle phase for fast LC analysis of selected pharmaceutical actives. In this thesis, a Nafion …
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Synthesis & retention mechanisms of novel mixed mode stationary phase for detection of specific polar low molecular weight biological samples
… coupled with boron-doped diamond electrodes for electrochemical detection. The synthesis and characterization of the novel mixed mode stationary phases prepared in this work is an important contribution to the field as the materials prepared exhibited better performance than similar materials …
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A Polypyrrole/Sulfonated Calixarene Modified Electrode for the Electochemical Detection of Dopamine
… polypyrrole (PPy-C4S)modified electrode for the electrochemical detection ofdopamine (DA) is reported. the physical and electrochemical characteristics of the PPy-C4S film are discussed, the oxidation of DA and the PPy-C4S modified electrode is investigated and the mode in which DA us detected at …
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Physicochemical Characterization of Creatine
… ion-pairing HPLC with UV- photometric detection was utilized. However, not a single study was utilized electrochemical detection tor the determination of creatine in aqueous and biological samples. Electrochemical detection not only offers superior sensitivity and limits of detection …
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Development of a Multi-Component Biosensor for Recombinase Polymerase Amplification-CRISPR/Cas12a-Based Detection of Fusarium oxysporum f. sp. cubense tropical race 4
… that integrates molecular diagnostics and electrochemical detection for sensitive and portable detection of Foc TR4 DNA. The system combines microneedle-based DNA extraction, Recombinase Polymerase Amplification (RPA), Clustered Regularly Interspaced Short Palindromic Repeats …
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Square-wave voltammetry detection for capillary electrophoresis
… by The lack of a generally applicable, Sensitive detection method. This Ph.D. project's aim was to develop such a method using electrochemical detection. After an initial review of the work done in electrochemical detection (ECD) for CE, it was determined that of the system that had been report …
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