Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Elastin Like Peptides"”.
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Non-equilibrium Dynamics of Nanoscale Soft Matter Deformation
Life is soft. From the fluid-like structure of lipid bilayers to the flexible folding of proteins, the realm of nanoscale soft matter is a complex and vibrant area of research. The lure of personalized medicine, advanced sensing technology, and understanding life at a fundamental level pushes …
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Computational Amide I Spectroscopy from the ground up : building and benchmarking new tools to study disordered peptide ensembles
… for intrinsically disordered proteins and peptides (IDPs) which possess inherent structural disorder in their functional forms. A prototypical example is elastin, a disordered structural protein that provides elastic properties to skin, lungs, and other connective tissues. In such cases, …
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Molecular structure, hierarchical assembly and stimuli-responsive mechanics of tropoelastin and elastin biomaterials
The elastin polymer, assembled from its molecular precursor tropoelastin, is the dominant component of elastic fibers, which confer elasticity and structural integrity to skin, lung, connective and vascular tissue. Historically, elastin's dynamic nature has precluded traditional approaches such as …
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Elastin-Like Peptide Dendrimers: Design, Synthesis, and Applications
Elastin like peptides (ELPs)—derived from the protein elastin—are widely used as thermoresponsive components in biomaterials due to their LCST (lower critical solution temperature) behavior at a characteristic transition temperature (Tt). While linear ELPs have been well investigated, few reports …
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Stimuli-Responsive Peptide-Based Biomaterials: Design, Synthesis, and Applications
… Composed of different amino acids, peptides can be designed with numerous sequences, providing flexibility and tunability in biomaterials. Peptides are easy to modify with small molecule drugs, inorganic components, and polymer chains to access multiple functions and tune properties …
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Expanding the genome editing toolbox for biomedical applications
… delivery methods, including DNA origami (DO), elastin-like polypeptides (ELPs), and sperm-mediated delivery. We showed that DO nanostructures were efficiently taken up by zygotes and crossed both the ZP and plasma membrane. In contrast, ELPs and mouse sperm failed to deliver the gene editing …