Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Ectromelia"”.
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The Role of the Complement System in Mousepox Infection
… including a complement regulatory protein. Ectromelia virus provides a mouse model for human smallpox infection where the virus and the host's immune response have also co-evolved. Using this model, we investigated the role of the complement system in a poxvirus infection. Ectromelia virus …
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Contribution Of Non-Classical Antigen Presentation To Cd4+ T Cells During Orthopoxvirus Infection
… the mechanisms of MHCII processing used during ectromelia infection, the causative agent of mousepox and a close relative of smallpox and monkeypox. First, we determined that whole poxvirions are refractory to processing via the classical exogenous pathway and that use of this pathway alone does …
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Molecular and evolutionary analysis of a gene conserved in most Orthopoxviruses
… cowpox (2 strains), taterapox, camel pox and ectromelia viruses. For every species gerbilpox virus was the nearest neighbour, suggesting that taterapox virus may be the species most closely related to the common ancestral Orthopoxvirus. Within the variola and cowpox virus species there was …
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Vaccinia virus BTB-Kelch proteins
… was selected as a starting point because the ectromelia virus (ECTV) orthologue of A55, ECTV EVM150, inhibits NF-κB signalling. Consistent with this, A55, C2 and F3 all inhibit NF-κB signalling pathway by diminishing p65 nuclear translocation. Specifically, A55 associates with importin KPNA2 …