Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 57 for “"Ectoderm"”.
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Inhibitory Control of Neural Differentiation in Explants of Rana Pipiens Gastrula Ectoderm
Made available in DSpace on 2014-12-04T22:46:13Z (GMT). No. of bitstreams: 1 6003902.pdf: 2144297 bytes, checksum: 284a504d8631cde70d658a32de811242 (MD5) Previous issue date: 1960
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Germ lineage specification from a pluripotent primitive ectoderm-like substrate: a role for cell-cell contacts.
… of gastrulation, in which pluripotent primitive ectoderm cells form the three germ lineages, mesoderm, ectoderm and endoderm under the control of complex signalling and environmental cues. This process can be modelled using embryonic stem cells, which have proven to respond to embryologically …
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The Role of Pax6 in Lens Placode Formation
… Fn1. Deletion of Pax6 from the lens-forming ectoderm prevented placode formation without altering cell proliferation or volume. <italic>Pax6<super>CKO</super> </italic>ectoderm expanded, rather than being constrained to a constant area, as normally occurs during lens placode formation, and …
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Purification, identification and characterisation of signals directing embryonic stem (ES) cell differentiation : a thesis submitted to the University of Adelaide for the degree of Doctor of Philosophy / Michael David Bettess.
… and identification of the early primitive ectoderm-like (EPL) cell induction signals within the medium conditioned by the human hepatocellular carcinoma cell line HepG2 and the localisation of the signals that induce EPL cell and primitive ectoderm formation.
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The evolution and function of pharyngeal arch signalling centres in jawed vertebrates
… when pouches of foregut endoderm contact surface ectoderm on either side of the embryonic vertebrate head. In fishes, endodermal pouches fuse with surface ectoderm to form gill slits. Once delineated, pharyngeal arches undergo morphogenesis and differentiation, giving rise to skeletal elements of …
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Short-Range Inter-Blastomere Signaling Specifies Ectodermal Fate and is Required for Skeletal Patterning in the Sea Urchin
… skeletal rods, and patterning inputs from the ectoderm, which secretes signals directing the growth and shape of the skeleton. To understand patterning of the skeleton therefore, the specification events behind these two processes must be understood separately, and then connected in order to …
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Assessment of chromatin activity in mouse and human tissues
… detected in three tissues examined; embryonic ectoderm, an embryo-derived tissue, and two extraembryonic tissues, extraembryonic ectoderm and ectoplacental cone. Embryonic ectoderm and extraembryonic ectoderm nuclei possessed comparable levels of DNAse I sensitivity while ectoplacental cone was …
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Role of Xenopus Pitx3 during early development.
… mesoderm, a crescent of anterior sensorial ectoderm, and a discrete spot which is fated to form Rathke's pouch. xPitx3 is expressed throughout lens induction in the presumptive lens ectoderm, lens placode, and later in differentiating lens. During tailbud stages, xPitx3 is also expressed …
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Revealing a Non-canonical Role of Anti-apoptotic MCL-1 in Early Embryonic Development
… into the three embryonic germ layers- ectoderm, mesoderm, and ectoderm. These data suggest that in addition to MCL-1’s required antagonism of cell death by the C-terminal region, MCL-1’s N-terminus is required for efficient cellular differentiation, potentially by facilitating MCL-1’s …
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The effects of BMP4 on different in vitro models for mouse gastrulation and neural induction
… germ layers: the mesoderm, endoderm and ectoderm. In the mouse embryo, gastrulation starts with a group of asymmetrically positioned cells expressing a group of genes that include T/Brachyury. These cells undergo a directed epithelial to mesenchymal transition (EMT) that gives rise to the …
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Effects of low oxygen culture on pluripotent stem cell differentiation and teratoma formation
… to the three germ layers, endoderm, ectoderm, and mesoderm and to cardiomyocytes and assessed residual PSC within differentiated populations. Low P02 drastically affects differentiation of PSC to the three germ layers and cardiomyocytes. Overall, differentiation was higher to …
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ONTOGENESIS OF MURINE NEURAL CREST DERIVATIVES
… domain within the neural and non-neural ectoderm. This domain is generated along the anterior-posterior axis-giving rise to many different cell types. The key difference between cranial and trunk neural crest is the ability of cranial neural crest to give rise to mesectoderm. However the …
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Developing a stem-cell system of embryonic development organised by a morphogen signaling centre
… the three germ layers: mesoderm, endoderm, and ectoderm are specified. Bone morphogenetic protein 4 (BMP4), secreted from the extraembryonic ectoderm is required for gastrulation to start whereby it activates downstream signaling molecules wingless inhibitor 3 (WNT3) and Nodal in a concentration …
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FROM A PLACODE PROGENITOR PLATFORM TO A TRIGEMINAL GANGLION ORGANOID: MODELLING SENSORY DEVELOPMENT AND FUNCTION IN VITRO
… brain. Developmentally, it originates from an ectodermal population named pre-placodal ectoderm, which is marked by the expression of the transcription factor SIX1, and which gives rise to most of the facial peripheral nervous system. The intermediate region of the pre-placodal ectoderm later …
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The Role of FGFR4 in Trigeminal Placode Cell Development
… in trigeminal placode cells remaining in the ectoderm that would have normally begun migration into the mesenchyme. These results show that FGFR4 is involved in trigeminal placode cell delamination.</p>
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Mechanical mapping of lineage boundaries in the developing Xenopus laevis embryo
… regions were both stiffer and more viscous than ectoderm cell regions, and that this endoderm region was more elastic dominated than the ectoderm region. I found a clear correlation between local mechanical properties and stem cell fate choice/lineage restriction during embryonic development *in …
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Molecular Basis of Vertebrate Embryonic Migration
… of cells where the three primordial layers, the ectoderm, mesoderm and the endoderm are one on top of the other. The three germ layers will go on to form all the tissues and organs of the embryo. For example, the ectoderm will give rise to epidermis and the nervous system; the mesoderm to …
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Developmental and Molecular Functions of Plakophilin-3
… in mice producing corresponding reductions in ectodermal integrity. In tissue, cellular and intracellular contexts where plakophilin-3 is not at the desmosomal plaque, little is known about its functions in the cytoplasm or nucleus, where it also localizes.</p> <p>My work employed embryos of …
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OOGENESIS IN TUBULARIA LARYNX AND TUBULARIA INDIVISA (HYDROZOA, ATHECATA)
… indivisa, interstitial cells proliferate in the ectoderm of the gonophore stalk and peduncle of the raceme and migrate in the endoderm to the apex of the young gonophore buds where they proliferate in the endoderm to form the entocodon and germ cell mass. Eggs are produced sequentially in the …
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Directed differentiation of endodermal cells from mouse embryonic stem cells
… endoderm and other germ cell layers such as ectoderm and mesoderm. These cells produced insulin and C-peptide and secreted insulin in a glucose responsive manner. However, they seem to lack mature insulin secretion mechanism. There was a production of hepatocyte markers (AFP-2 and …
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