Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Early Onset Dementia"”.
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Living with early-onset dementia: thematic analysis of dementia blogging and autobiography
<b>Background </b><br/>Dementia is the biggest cause of death in the United Kingdom (Matthews, 2016). Early-onset dementia (EOD) is a subset of the dementias affecting people between the ages of forty-five to sixty-five (Mercy, 2008). People with early-onset dementia (PwEOD) can find themselves …
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Serpin polymers enforce molecular filtration in the endoplasmic reticulum
… of these serpins leads to cirrhosis and early-onset dementia respectively. Molecular mechanisms of these diverse pathologies remain incompletely understood. Utilising a range of advanced live-cell imaging techniques I showed that serpin polymers undergo a liquid:solid phase transition, …
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Co-Becomings in Creative Music Workshop Practices
… practice in three diverse sites including an early years classroom, an online music making group for young autistic people and a music group for people with early onset dementia and their families. The inquiry is guided by areas of curiosity which include investigation of material encounters …
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Gain And Loss Of Progranulin Have Opposite Effects On Autophagy
… degeneration (FTLD), the most common type of dementia after Alzheimer’s disease (AD), whereas homozygous mutations result in neuronal ceroid lipofuscinosis (NCL), an infantile onset disease. During my Ph.D thesis, I found that hepatic PGRN overexpression in mice results in autophagy impairment …
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Modeling HIV-1 Infection in the Brain: The Effect of the Blood-Brain Barrier
… to be associated with these disorders, such as early-onset dementia. \textit{In vivo} study of HIV infection in the brain is extremely difficult, and thus mathematical modeling can help to further the analysis of the viral dynamics of HIV in the brain. In this dissertation we develop a …
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The incidence of mental ill-health in adults with intellectual disabilities
… Valk et al, 1997) have measured the incidence of dementia and only one study (van Schrojenstein Lantman-de Valk et al, 1997) has attempted to measure the incidence of affective disorder. No study has measured the overall incidence of mental ill-health in this population. Similarly, although the …
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Advancing knowledge into the clinical assessment of dementia.
… cognitive and social abilities in people with dementia and learning disabilities. In Chapter 1, normal agemg was discussed, distinguishing it from abnormal ageing and highlighting the problems it brings in terms of physical and psychological factors. Normal memory was also discussed and how the …