Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"EWAS"”.
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DNA Methylation: Methods and Analyses
Epigenome-wide Association Studies (EWAS) have been a popular method to investigate the genome over the past decade. From these experiments, more than 75,000 samples have been assayed using the high-throughput, cost-effective HumanMethylation450 microarray (450k) developed by Illumina. With the …
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Bioinformatics analysis of epigenetic variants associated with melanoma
… the power of Epigenome-wide association studies (EWAS). Over the last couple of years comprehensive sequence data sets have been generated, allowing analysis of genome-wide activity in cohorts of different individuals to be increasingly available. Finding associations between epigenetic variation …
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Early Life Determinants of Metabolic and Reproductive Health
… conducting phenome-wide association studies (PheWAS), which is used to explore the extent to which both BMI and sex hormone exposure act as mediating factors to explain the link between earlier puberty and heightened reproductive health risks. I go on to examine mechanisms linking early life …
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Mixture Model Approaches to Integrative Analysis of Multi-Omics Data and Spatially Correlated Genomic Data
<p>Integrative genomic data analysis is a powerful tool to study the complex biological processes behind a disease. Statistical methods can model the interrelationships of the involved gene activities through jointly analyzing multiple types of genomic data from different platforms (vertical …