Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 48 for “"ETO"”.
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Characterisation of the leukaemia-associated ETO homologues
… in the expression of the chimeric protein AML1-ETO. AML1 is a transcription factor of crucial importance during hematopoiesis. The function of the fusion partner eight-twenty-one (ETO) is much less understood. The aim of this thesis was to characterise ETO and its two homologues, myeloid …
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Development of the Advanced Emitter Turn-Off (ETO) Thyristor
… semiconductor device, the emitter turn-off (ETO) thyristor, which is targeted to improve the limitations of the present high power devices. Major improvements in electrical and mechanical designs of the ETO for high power and high frequency operation are proposed which result in improved …
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The role of the leukemia-associated ETO homologue repressors in hematopoiesis
The fusion protein AML1-ETO is observed in acute myeloid patients with the chromosomal translocation t(8;21). Cells with this chimeric protein have impaired granulocytic and erythroid differentiation with accumulation of myeloblasts. The transcriptional co-repressor ETO (Eight Twenty One) was …
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AML1/ETO Downregulates the Transcription Factor PU.1 in Acute Myeloid Leukemia
AML1-ETO is a fusion protein encoded by the translocation t(8;21) and found in 15% of acute myeloid leukemia patients. Here, we report a negative functional impact of AML1-ETO on the transcriptional activity of PU.1, an important transcription factor for normal myeloid differentiation. We have …
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Proto-oncogene c-jun expression is induced by AML1-ETO in a JNK dependent manner:possible role in the pathogenesis of acute myeloid leukemia
… translocation and results in the AML1-ETO fusion protein. Overexpression of AML1-ETO in NIH3T3 cells leads to increased phosphorylation of Ser63 in c-Jun, which is generally JNK dependent. The role of the JNK signaling pathway for the functional properties of AML1-ETO is, however, …
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Tuning Strong Correlated Properties in EuTiO3 Thin Films Grown by Pulsed Laser Deposition
… such as superconductivity, multiferroicity, magnetoresistivity, and photovoltaics. To achieve and enhance these existing functionalities in perovskite oxides, control and tailor of strong coupling between structural degrees of freedom and correlated order parameters is required. One typical …
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Advanced Semiconductor Device and Topology for High Power Current Source Converter
… technologies, a symmetrical emitter turn-off (ETO) thyristor is developed that shows superior switching performance, high power rating and reverse voltage blocking capability. The on-state characteristics, forced turn-on characteristics, forced turn-off characteristics and the load-commutated …
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Analysis of senescence-like growth arrest induced by RUNX1 and its fusion derived oncoproteins
… in the truncated C-terminal fusion protein RUNX1-ETO (AML1-ETO). The potential to drive senescence is retained by the deletion mutant RUNX1-ETO[]469 which lacks critical corepressor binding sites suggesting that the repression of target genes may be a primary mechanism implicated in RUNX1-ETO …
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Tertiary N-acyl phosphoramidates : a mechanistic study of their formation and collapse in reactions with nucleophiles
… (X = Br, Cl, F) with the conjugate base of (EtO)₂P(O)NHMe (IX) yields three products: PhCO₂Et (4), PhC(O)NHMe (5) and (PhCO)₂NMe (6). (5) and (6) are formed via the initial rapid formation of (EtO)₂P(O)-NMe-C(O)Ph (IIIe), while (4) results from the E1cB related reaction of (EtO)₂P(O)NMe …
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Comparação de equações que estimam a evapotranspiração de referência (ETo) com o modelo de Penman-Monteith padrão FAO nas condições do município de Areia-PB
… was to compare the reference evapotranspiration (ETo), estimated by the Blaney & Criddle, Priestley-Taylor, Hargreaves & Samani and the class "A" Tank equations, with those estimated by the Standard FAO Penman-Monteith model in Areia-PB conditions. To achieve this goal, average monthly weather …
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The effect of processing method of broiler litter on pasteurization, nitrogen loss and nitrogen utilization by sheep
… depths of 0.63 and 2.54 cm; and ethylene oxide (ETO) fumigation for 30 min. or longer. Moisture and uric acid nitrogen were lowered (P < .01) for dry heat and the PFA processes. Autoclaving and PFA addition followed by dry heating lowered (P < .01) NPN. Ammonia nitrogen was reduced (P < .01) by …
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Application of High-Power Snubberless Semiconductor Switches in High-Frequency PWM Converters
… Thyristor (IGCT) and the Emitter Turn-Off (ETO) thyristor. These new devices all feature high switching speed and the capability to turn off without the requirement for a turn-off snubber. With these new device technologies the high-power field of power electronics can realize dramatic …
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Electrical, Magnetic, Thermal Modeling and Analysis of a 5000A Solid-State Switch Module and Its Application as a DC Circuit Breaker
… semiconductor switch, the emitter turn-off (ETO) thyristor as the main interruption switch. In order to meet the requirement of being a high-current circuit breaker, ETO parallel operation is needed. Therefore the major effort of this dissertation is dedicated to the development of a …
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Inactivation of Salmonella enterica and Enterococcus faecium on Whole Black Peppercorns and Cumin Seeds Using Steam and Ethylene Oxide Fumigation
… include steam treatments and ethylene oxide (EtO) fumigation. The objectives of this research were to identify the effectiveness of a lab-scale steam apparatus and a commercial EtO process on the inactivation of Salmonella enterica or Enterococcus faecium NRRL B-2354 inoculated whole black …
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Innovative GTO Thyristor Based Switches Through Unity Gain Turn-Off
… dissertation. The Emitter Turn-Off Thyristor (ETO) is a new family of high power semiconductor devices that is suitable for megawatt power electronics application. ETOs with voltage and current ratings of 4.0~6.0 kV and 1.0~4.0 kA, have been developed and demonstrated. These power levels are …
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Determining Water Requirements in Turfgrass Systems
… and determine the reference evapotranspiration (ETo) percent replacement that maximizes bermudagrass (Cynodon dactylon [L.] Pers.) establishment from seed and whether Turfgrass Water Conservation Alliance qualified cultivars require less water to establish from seed. From the cultivars evaluated, …
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A lightweight method for improving coordination in distributed, high-variability product companies
… sites-based on lessons from engineer-to- order (ETO) operating models. By examining contemporary trends in ETO and identifying several generalizable tensions, this study outlines key parameters that distinguish dynamic coordination needs from those embedded in conventional process improvement …
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Drought and salinity tolerance of cool-season turfgrasses
… treatments, 40%, 60% and 80% evapotranspiration (ETo) from 2018 to 2020. Overall turfgrass quality, minimum irrigation requirement for maintaining the acceptable quality, and length of time to maintain acceptable quality were determined for each entry. The amount of irrigation needed to maintain …
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