Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"ETB receptor"”.
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Importance of MAPK and PKC in cerebrovascular endothelin receptor changes
… peptide that exerts its effect through two receptors; the endothelin type A (ETA) and type B (ETB) receptor. The contractile ETA receptor is localized on smooth muscle cells in the vascular wall, while the ETB receptors are mainly situated on endothelial cells, mediating vasodilatation. The …
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Modeling Alterations In Nociception Following Repeated Vaso-Occlusive Episodes
… in female rats via modulation of endothelin-B (ETB) receptor. This thesis focuses on the hypothesis that exposure to ET-1 early in development alters nociception later in development via sex-dependent regulation of the ETB receptor. Three specific aims were undertaken to test this hypothesis. In …
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Endothelin-1 is over-expressed in Amyotrophic Lateral Sclerosis and induces Motor Neuron cell death
… and reactivity. We found that both ETA and ETB receptors are enriched in astrocytes in MSCs. The ET-1 toxic effect was mimicked by ET-3 (100 nM) and sarafotoxin S6C (10 nM), two selective agonists of endothelin-B receptors, and was not additive with that of ET-3 suggesting the involvement of …
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Vascular Endothelin and Angiotensin Receptors Regulation in Inflammatory Arterial Disorders
… of vascular endothelin and angiotensin receptors. The receptor changes were studied in subcutaneous resistance arteries in patients with different degrees of ischemic heart disease (IHD). In addition, patients with giant cell arteritis (GCA) were also investigated because of the massive …