Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"ERG3"”.
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Delineating the Upc2A Regulon in Candida glabrata
… exposure. Only three genes (UPC2A, ERG25, and ERG3) were found to be downregulated in the absence of UPC2A. Sixteen genes were commonly upregulated in response to SBIs’ treatment in a Upc2A-dependent way, including ERG2, ERG3, and ERG11, the promoters of 10 of which were bound by Upc2A. A total …
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An Investigation into Clinically Relevant Determinants of Azole Resistance in Candida albicans
… in the ergosterol biosynthesis genes, ERG11 and ERG3, encoding a C-5 sterol desaturase, also contribute to clinical azole resistance in C. albicans. The interplay of these mechanisms can result in azole-resistance, treatment failure, and ultimately, poorer outcomes in patients. Therefore, to …
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The role of GATA-1 isoforms in haematopoiesis
… that that the chromosome 21 candidate gene Erg3 was upregulated in trisomic cells and that expression of GATA-1s appeared to confer a selective advantage in the presence of trisomy 21. However, no clear mechanistic reasons for the selective advantage could be identified. Overall, these …