Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"ER-to-Golgi trafficking"”.
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Dissecting the Physiological Roles of ULK1/2 in the Mouse Brain
… elegans UNC-51 and Drosophila melanogaster Atg1 are redundant serine/threonine kinases that regulate flux through the autophagy pathway in response to various types of cellular stress. C. elegans UNC-51 and D. melanogaster Atg1 also promote axonal growth and defasciculation, and …
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ABCB6 Is a Porphyrin Transporter with a Novel Trafficking Signal That Is Conserved in Other ABC Transporters
<p>The ATP-binding cassette (ABC) transporters play an important role as a barrier to protect cells from the accumulation of toxic xenobiotics and metabolites due to their ability to translocate a wide array of compounds across lipid bilayers. However, many ABC transporters, especially the ones …
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A New Approach To Identifying Effectors and Regulators of Small GTPases
Secretion and endocytosis are essential processes in eukaryotic cells, executed and tightly regulated by the cell’s endomembrane system. It is widely accepted that small GTPases of the Ras superfamily are major regulators of membrane trafficking and signalling, ensuring specificity and efficiency …
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The role of Atgolgin-84A at the plant ER-Golgi interface
The eukaryotic cell is compartmentalised into an endomembrane system organised into several organelles. Some of these organelles, namely endoplasmic reticulum (ER) and Golgi bodies, are part of a so-called secretory pathway where vital cell components travel to reach the correct final destination …
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Defining the Cellular and Molecular Basis of Spondyloepiphyseal dysplasia tarda
… vesicles from the endoplasmic reticulum (ER) to the Golgi apparatus en route to the plasma membrane, other intracellular organelles and the extracellular matrix. After folding, newly synthesized proteins reach the Golgi apparatus through COPII carriers. COPII vesicles bud from sub-domains …