Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"ER-mitochondria contacts"”.
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Testing roles of Hereditary Spastic Paraplegia (HSP) proteins in organization of axonal endoplasmic reticulum (ER) and ER-mitochondria contacts
The Hereditary Spastic Paraplegias (HSPs) are a group of genetically heterogeneous, neurodegenerative and neurodevelopmental diseases characterised by spasticity and lower limb weaknesses. Some known causative genes imply the importance of endoplasmic reticulum (ER) function and morphogenesis in …
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LINOLEIC ACID UNLEASHES THE ANTI-TUMOR POTENTIAL OF CD8 T CELLS BY PROMOTING METABOLIC REPROGRAMMING
T cell therapy (ACT) has achieved unprecedented clinical results in the treatment of cancer, but scarce intra-tumor infiltration, persistence and function of adoptively transferred T cells limit its efficacy, especially in solid tumors. Metabolic constraints imposed by the tumor microenvironment …
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Linking Architecture and Function of Endoplasmic Reticulum - Plasma Membrane Contact Sites
… network of membrane contact sites (MCS) and thereby promote cellular functions such as lipid metabolism, signalling and organelle biogenesis. The formation of cortical endoplasmic reticulum (cER) - plasma membrane (PM) contacts in budding yeast cells is mediated by a set of six conserved …