Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"ER-Lysosome"”.
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The role of CASM in the endolysosomal damage response
Lysosomes are the major degradative organelle within the cell, where they play integral roles in degradative processes such as macroautophagy and phagocytosis, in addition to engaging in other key cellular processes such as antigen presentation. Endolysosomal (hereafter referred to as lysosomal) …
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Parkinson's Disease-Associated Protein VPS13C Regulates Phospho-Rab10-Mediated Lysosomal Function in Human iPSC-Derived Dopaminergic Neurons
Neurodegenerative diseases are progressive disorders with age as the greatest risk factor. Parkinson’s disease (PD) is the most common movement disorder and the second most common neurodegenerative disease after Alzheimer’s disease. A stark increase in the incidence of neurodegenerative diseases is …
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Ca2+ signalling between the endoplasmic reticulum and lysosomes
Ca2+ is a universal and versatile intracellular messenger, regulating a vast array of biological processes due to variations in the frequency, amplitude, spatial and temporal dynamics of Ca2+ signals. Increases in cytosolic free Ca2+ concentration ([Ca2+]c) are due to influx from either an infinite …