Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"ER membrane protein complex"”.
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Characterization of Host Factors and Anti-viral Compounds for Diverse Mosquito-borne Flaviviruses
<p>Our ability to convert basic knowledge into robust anti-viral therapeutics requires discovery of novel host-virus interactions as well as an informed anti-viral discovery pipeline. We used a genome-scale RNAi-based screen followed by a chemical screen of FDA-approved therapeutics to identify …
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Mechanisms of multipass membrane protein biogenesis
… reagents to improve efficiency. Semi-permeable membranes facilitate autonomy via an outer barrier (plasma membrane) and enclose functional hubs (organelles) to efficiently carry out biological processes. However, cells do not live in isolation and must communicate with neighboring …
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Membrane protein biosynthesis at the endoplasmic reticulum
The biosynthesis of integral membrane proteins (IMPs) is an essential cellular process. IMPs comprise roughly 20-30% of the protein coding genes of all organisms, nearly all of which are inserted and assembled at the endoplasmic reticulum (ER). The defining structural feature of IMPs is one or more …