Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 17 of 17 for “"EPIC-Norfolk"”.
-
The Epidemiology of Cognitive Function In a Community Based Population. The EPIC-Norfolk Study
… Prospective Investigation into Cancer in Norfolk (EPIC-Norfolk) is a prospective population study of 25 639 men and women aged 40–79 years first recruited in 1993-1997, who attended a health examination. Subsequent follow-ups have involved self-report of health and lifestyle and further …
-
Risk assessment for osteoporotic fractures among men and women from a prospective population study: the EPIC-Norfolk study
… European Prospective Investigation into Cancer (EPIC)-Norfolk study, which is a large population-based prospective study started in 1993. About 25,000 men and women were assessed at baseline and about 15,000 of them returned for a second examination 4 years later. All participants are followed up …
-
The epidemiology of hospital admissions in a general population: record linkage of hospital episode statistics to the European Prospective Investigation of Cancer (EPIC-Norfolk) cohort
… European Prospective Investigation of Cancer in Norfolk (EPIC-Norfolk), a community-based cohort of 25,639 men and women aged 40-79 at recruitment between 1993-1997 and followed up to the present. Participants completed a lifestyle questionnaire and attended a clinic where measurements and blood …
-
Meat consumption and type 2 diabetes: investigating heterogeneity and potential causal mechanisms
… intake) and the outcome (incident T2D) in the EPIC-Norfolk study, a population-based cohort study of over 25,000 participants. I worked on improving case ascertainment of T2D as the primary outcome in my analyses. I updated T2D case ascertainment in EPIC-Norfolk by linkage of multiple external …
-
Lipoprotein(a) and the risk of vascular disease
… European Prospective Investigation of Cancer – Norfolk (EPIC-Norfolk) study (2200CHD cases, 2200 controls) 3. The Pakistani Risk of Myocardial Infarction Study (PROMIS) (1800 MI cases and 1800 controls) 4. Systematic quantitative reviews of published epidemiological studies Results: ERFC data - …
-
Application of biomarker-based assessment of dietary patterns to nutritional epidemiology: observational and interventional investigations with a focus on the Mediterranean diet and type 2 diabetes
… dietary pattern. Chapter 3: I used the EPIC-InterAct case-cohort study which measured nutritional biomarkers at scale (~13,000 subcohort participants and ~9,000 incident type 2 diabetes cases) to evaluate the utility of combining them into biomarker scores predictive of adherence to …
-
The associations of stroke risk and risk factors with dietary intakes and biomarkers of magnesium and protein
… and women, a representative sub-sample of the EPIC-Norfolk cohort, aged 39-80 and 234 older men and women, aged 65-79, from the NU-AGE study. Multiple regression analysis and cox-proportional hazards model were used to assess associations between dietary magnesium and protein intakes, with BP, …
-
Dairy products and cardio-metabolic health: aspects from nutritional, molecular and genetic epidemiology
… Using data from the large Fenland (n~12,000) and EPIC Norfolk (n~25,000) studies, I investigated associations of total and types of dairy consumption with markers of metabolic risk and adiposity as potential pathways to cardio-metabolic disease. The analyses showed differential associations of …
-
Epidemiological investigations of biomarker and dietary relationships with osteoporosis and fracture risk
… associations with fracture risk in a sub-set of EPIC-Norfolk participants. An additional aim was to explore means of limiting the impact of measurement errors on the association between vitamin C and bone health. The main results showed significant associations between higher intakes of vitamin …
-
Ultra-processed foods and cardiometabolic health
… comparison, and a prospective analysis in the UK EPIC-Norfolk cohort. The research presented in this dissertation revealed consistent associations between UPFs and adverse cardiometabolic health. The results of the systematic review and meta-analyses of chapter 2 provided the first systematic …
-
Gender, diet quality and obesity: economic and social determinants, and their interactions, in older adults
… examined in over-50s from the population-based EPIC-Norfolk cohort for associations with quantity and variety of fruit and vegetable intake, as proxies for healthful eating. FH was inversely associated with variety, more than quantity, independent of socioeconomic status (SES). Given the …
-
Weighting and moment conditions in Bayesian inference
… the MCMC literature. We analyse data from the EPIC-Norfolk cohort study to investigate the associations between saturated fatty acids and incident type-2 diabetes. However, ignoring the sampling is not always beneficial. For a variety of popular problems, weighting offers the potential for …
-
The development of novel tools for the assessment of UK firefighter nutritional status for use in a multi-component worksite nutrition intervention programme
… via population specific modification of the EPIC-Norfolk FFQ and validated against three 24hr recalls. Correlations between the methods were significant (p< 0.01) for energy (r=0.42), carbohydrate (r=0.42), protein (r=0.42), fat (r=0.35), fibre (r=0.34), saturated fatty acids (r=0.36), …
-
A Population-Level Approach to Dementia Risk Reduction
… prediction scores within the population-based EPIC-Norfolk study, 70 to 90% of new dementia cases were found to occur in people classified as being at ‘normal risk’ at baseline, over three decades of follow-up. Accepting the need for a population-level approach, the next step (Chapter 3) …
-
Combined associations of diet quality, physical activity, and their changes over time with cardiometabolic risk and mortality
… (DM) and CVD were evaluated, using data from the EPIC-Norfolk study with nearly three decades of follow-up. With repeated measurement of health behaviours among 9,349 participants, Mediterranean diet score (MDS) and physical activity energy expenditure (PAEE) were derived. Both baseline status of …
-
Towards an Understanding of Sedentary Time and Physical Activity in Older Adults: Informing the Development of Future Behavioural Interventions
… in participants from the population-based EPIC Norfolk cohort study. Physical activity and sedentary time were assessed using accelerometers. Physical function measures included hand grip strength, usual walking speed and chair stand speed. Health-related quality-oflife (Hr-QoL) was …
-
Investigating the Relationship between Markers of Ageing and Cardiometabolic Disease
Human ageing is accompanied by characteristic metabolic and endocrine changes, including altered hormone profiles, insulin resistance and deterioration of skeletal muscle. Obesity and diabetes may themselves drive an accelerated ageing phenotype. Untangling the causal web between ageing, obesity …