Global ETD Search
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Showing 1 to 4 of 4 for “"EP receptor"”.
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PGE2 Receptor Subsets Mediate HCG Regulation of the Plasminogen Activator/Plasmin System in Primate Periovulatory Follicles
… is PGE2 mediated.</p> <p>There are four PGE2 receptors: EP1, EP2, EP3 and EP4. To determine which PGE2 receptors are present in monkey periovulatory follicles, granulosa cells and whole ovaries were collected 0, 12, 24, and 36 hours after administration of an ovulatory dose of human chorionic …
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Regulation of Endogenous Excitatory Neurotransmitters by Isoprostanes
… 8-isoPGE2 caused a concentration-dependent attenuation of retinal glutamate and glutamine levels. For instance, 8-isoPGE2 (1 μM and 100 μM) significantly (p<0.001) attenuated glutamate levels by 33.9% and 48.0%, respectively. 8-isoPGE2 (100 μM) inhibited (p<0.01) retinal glutamine …
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Role of Prostaglandin E2 In The Regulation of Pancreatic Stellate Cells Hyper Activity Associated With Pancreatic Cancer
… (MMP) genes. I further identified the PGE2 EP receptor responsible for mediating these effects on PSC. Using genetic and pharmacological approaches I identified the receptor required for PGE2 mediates PSC hyper activation. Treating PSC with Specific antagonists against EP1, EP2 and EP4, …
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The Prostaglandin E2 Receptor Subtype 3E and its involvement in tauopathies
… of Alzheimer’s disease and tauopthies. Epidemiological studies report a delay in the onset of Alzheimer’s in subjects using nonsteroidal anti-inflammatory drugs (NSAIDs). NSAIDs inhibit enzymes in the cyclooxygenase-2 (COX-2) pathway which play a key role in synthesising prostaglandin E2 …