Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"EMT pathway"”.
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Delineating metastasis in MSS colorectal cancer by single - cell RNA sequencing
… via the Epithelial-Mesenchymal Transition (EMT) pathway. Immune cell analysis highlighted significant differences in the proportion and functional status between primary and metastatic sites. Correlation analyses suggest that there may be crosstalk between CAFs and immune cells that …
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Mechanism of Metformin Action in Dermal Fibroblasts
… expression of epithelial-mesenchymal transition (EMT) genes and markers. The primary EMT pathway regulated by metformin was SMAD3, which was decreased by metformin treatment resulting in decreased collagen I gene expression. Metformin also reduced total collagen secretion in low glucose …
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PLGA-DS reverses chemoresistance in malignant mesothelioma by targeting hypoxia induced cancer stem cells
… cells (CSCs) by hypoxia. Both hypoxia and NF-κB pathway plays a pivotal role in the maintenance of stemness in hypoxia-induced CSCs leading to upregulation of anti-apoptotic signalling, chemo-radiation resistance and metastasis. Therefore, the development of drugs targeting hypoxia-NF-κB-CSCs …