Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"EMT (epithelial-to-mesenchymal transition)"”.
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Μελέτη του σηματοδοτικού μονοπατιού ILK/p-Akt στο ηπατοκυτταρικό καρκίνωμα του ανθρώπου : συσχέτιση με την έκφραση παραγόντων που εμπλέκονται στην απόπτωση και στον κυτταρικό πολλαπλασιασμό
… της επιθηλιακής προς μεσεγχυματική μετατροπή (EMT-epithelial to mesenchymal transition). Αυτό αποδεικνύεται από την απώλεια έκφρασης της E-καντχερίνης και τη μεταφορά της β-κατενίνης στον πυρήνα που οδηγούν σε απώλεια των κυτταρικών συνδέσεων από τη μεμβράνη καθώς και από την υπερέκφραση των …
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Role of ATRX in colorectal cancer metastasis
… has been established by the Myant lab as a mediator of plasticity and non-canonical cell states, TGFβ-induced epithelial-to-mesenchymal transition (EMT), and invasion in CRC. These characteristics are thought to promote aggressive and metastatic disease; therefore, the first aim of my project was …
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Epithelial to Mesenchymal Transition As A Predictor of Response to Polo-Like Kinase 1 Inhibition-Induced Apoptosis In Non-Small Cell Lung Carcinoma
… kinase 1 (PLK1), involved in the regulation of mitotic processes and the response to DNA damage, is overexpressed in NSCLC. Inhibiting PLK1 may be an effective treatment for NSCLC patients as it is involved in the mechanisms of resistance to several chemotherapy drugs. PLK1 inhibition or …
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A NOVEL BRAF SIGNALING CASCADE THROUGH p-21 ACTIVATED KINASES REGULATES THYROID CANCER CELL MOTILITY
… This fact has prompted thyroid research to focus on investigating the pathways that lead to pathogenesis with a goal to develop new therapeutics. If detected at an early stage, PTC is curable most of the time; however, for patients with aggressive and invasive forms of it, treatment …