Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"EMERIN"”.
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Emerin and inherited disease
(cont.) nucleus and at the nuclear surface.
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Lamin A and lamin C are differentially dysfunctional in autosomal dominant Emery-Dreifuss muscular dystrophy
… assay of in vitro synthesised A-type lamins and emerin was performed.Eight of the LMNA mutations (R50S, R133P, E358K, E358K+C<T1698, E361K, R527P, L530P, R541S and G602S) and the SNP C<T1698, when expressed in lamin A, exhibited a range of nuclear mis-localisation patterns from a wild type …
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A Nuclear Mechanoresponse to Morphogenesis Drives Acquisition of Neuroectoderm Lineage Competence During Pluripotent Cell Differentiation
… commitment to the neuroectoderm lineage. Emerin is a mechanosensitive, LINC-interacting, nuclear envelope protein that can regulate histone-modifying enzyme activity. Emerin knock-down also resulted in impaired neuroectoderm differentiation. Interestingly, perturbations of contractility or …
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Changes in the Oligodendrocyte Progenitor Cell Nuclear Lamina During Ageing
… localisation of the nuclear lamina protein emerin, occurring both with ageing and upon exposure to hydrogels of different stiffnesses. Knock-down experiments suggest that this changing localisation of emerin may play a causal role in the changing regenerative potential of OPCs. The potential …
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Understanding the adhesome network in primary and metastatic cutaneous squamous cell carcinoma
… of Mena regulates the phosphorylation of EMERIN and possibly affects histone methylation. Here, we propose a novel mechanism by which Mena may regulate metastasis during SCC progression.
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Single-Objective Tilted Light Sheet Illumination with Exchange-PAINT and Deep Learning for Fast, Accurate, and Precise 3D Single-Molecule Super-Resolution Imaging in Mammalian Cells
… nuclear lamina proteins lamin B1, lamin A/C, and emerin, and the microtubule protein alpha-tubulin. The single-objective dithered light sheet achieves a localization precision below ten nanometers in xy and below 12 nanometers in z, enabling a range of applications from nuclear protein …