Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"ELR"”.
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Analyzing the Safety Effects of Edge Lane Roads for All Road Users
… analyzes the safety effects of Edge Lane Roads (ELR) for all road users. This is important since ELRs can be a solution to many issues, such as alleviating congestion, increasing multimodality along roadways, and reducing maintenance costs. ELRs in both North America and Australia were observed. …
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Organelle remodeling and V-ATPase dynamics in the lysosome regeneration cycle
… as of lysosome reformation from endolysosomes (ELR), which together make up the regeneration cycle. It also includes a description of the sucrosome system used to study ELR. Chapter 2 describes the materials and experimental methods used throughout my research. In Chapter 3, I describe …
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Ras Intrinsic and Extrinsic Pathways in Human Cancer
… these cytokines hCXCL-8 (IL-8) belonged to the ELR+ CXC family of cytokines, suggesting that the entire family of ELR+ CXC cytokines may promote Ras driven tumorigenesis. Indeed, I found that expression of oncogenic Ras led to secretion of all ELR+ CXC chemokines in oncogenic Ras driven tumor …
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Effects of CXCL8 Overexpression on Tumor Cell Proliferation and Migration in an HNSCC Cell Model
… as chemokines. CXCL8 (Interleukin-8), a CXC ELR+ Chemokine mainly responsible for neutrophil chemoattraction, has beenimplicated in increased tumor proliferation, migration and angiogenesis. The current studytests the effects of CXCL8 on the tumor proliferation and metastasis. By genetically …
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Genome sequencing and phenotypic analysis of single cells in cancer
… polyfunctional heterogeneity in secretions of ELR+ CXC chemokines from single tumor and stromal cells and demonstrate how the true behavior of single cells can be hidden in bulk assays. We also describe assays to measure the growth kinetics of tens of thousands of single cells in parallel and …
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Uncovering the hidden mechanisms governing the transcriptional regulation of inflammation
… chemokine LOcus), was found to emanate from the ELR+ CXCL chemokine TAD and regulate the transcriptional activation of the pro-inflammatory ELR+ CXCL chemokines (IL-8, CXCL1, CXCL2 and CXCL3). By exploiting the pre-formed local 3D topology, UMLILO is able to epigenetically prime the chemokines …
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BIOLOGICAL AND TRANSDUCTIONAL EFFECTS OF ALLOSTERIC ANTAGONISTS ON THE ACTIVITY OF CHEMOATTRACTANT RECEPTORS
… the problem of redundancy generated by the ELR+ CXC chemokine-CXCR1/R2 axis. The present study demonstrated, that DF 2156A is a potent blocker of both CXCR1 and CXCR2 expressed on PMNs, lymphocytes, and cells transfectants with a IC50 in the range of 1 to 2 nM. Despite its potency on both …
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On-line shear and extensional rheometry of polymer melts in the extrusion process.
… dedicated software, and the extrusion line and ELR were fully instrumented allowing real-time process monitoring to be carried out by IBM compatible PCs via data acquisition hardware and software. The prototype OLR was developed by the re-design of several key features including an instrumented …
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On-line shear and extensional rheometry of polymer melts in the extrusion process.
… dedicated software, and the extrusion line and ELR were fully instrumented, allowing real‑time process monitoring to be carried out by IBM‑compatible PCs via data acquisition hardware and software. The prototype OLR was developed by the re‑design of several key features including an instrumented …
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Public Health Professionals’ Prepardness and Challenges In Implementing Certified Electronic Health Records Technology
… (SendSS) and the Electronic Lab Reporting (ELR) are still not linked for data entry directly into the systems. Bandwidth is an issue with speed of data transfers a significant concern. Health district leadership recommends that the MU would definitely make a positive impact on improving and …
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Malnutrition and intellectual development: a comparative follow-up study on the effects of early dietary supplementation in a population at risk.
… sducaticnal progrmns to provide sur,tc,ined elr~v2tion in t:-,e IQ scores of undsr-privilagad children, ood tho suggestion is-~ada that this failure could at least in p8rt be attrib~ted to the operation of nutritional factors ..
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An action research evaluation to understand and inform the role of the Integrated Care Pharmacist across health and social care
… and Rutland Clinical Commissioning Group (ELR CCG). Aim The aim of the study was to understand and inform this new role of the IC Pharmacist for ELRCCG and how to develop and sustain such a role. Methods A participatory mixed methods research strategy, which aligns with pragmatism as a …