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Showing 1 to 6 of 6 for “"EIF5A."”.
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Analysis of the Role of EIF5A in Mammalian Translation
… data identified eukaryotic initiation factor 5A (EIF5A) as novel regulator of MYC translation. eIF5A is a highly conserved translation factor that has been demonstrated to relieve ribosome pauses during translation elongation at 'difficult to translate' peptide sequences in yeast and bacteria. We …
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The role of eukaryotic initiation factor 5A and its cellular localization in developing Zea mays plant tissue.
… and leaf tissue have reinforced the idea that eIF5A has at least a secondary role in cellular proliferation and cell division. The interactions of eIF5A with numerous maize proteins identified through pull down analysis, have provided insight into the primary function of this elusive protein. …
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Understanding the Role of Hypusine Biosynthesis in Endocrine-Exocrine Crosstalk
… factor eukaryotic initiation factor 5A (eIF5A), when in its post-translationally modified “hypusinated” form, plays a role in pancreas development. The hypusination of eIF5A requires the rate-limiting enzyme deoxyhypusine synthase (Dhps) to post- translationally modify a critical lysine …
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Essentiality and Regulation of Deoxyhypusination in Trypanosoma brucei
… of eukaryotic initiation factor 5A (eIF5A). Hypusination, a post-translational modification, occurs via two enzymatic reactions. First, deoxyhypusine synthase (DHS) transfers the aminobutyl moiety of spermidine onto the eIF5A-lysine generating deoxyhypusine which is then hydroxylated …
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Proteomic approaches for the identification of biomarkers of beef tenderness from Longissimus thoracis muscles and plasma of young Limousin-sired bulls
… MYOZ3, BIN1 and OGN for WBSF; CACNA2D1, EIF5A, STBD1, WDR1 for tenderness; SOD1, PHKA1, ATP5F1C for chewiness; TPT1, SOD1, TPM3, HPX for stringiness; PHKG1, CORO6, ATP5F1A for flavour. Moreover, PHKA1 and STBD1 showed significant correlations with tenderness, chewiness, stringiness and …
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Eukaryotic Initiation Factor 5A2 (EIF5A2) Contributes to Ovarian Tumor Growth and Metastasis
<p>Ovarian cancer has the highest mortality rate among all gynecological malignancies due to lack of effective biomarkers for early diagnosis. The majority of ovarian cancer patients are already at an advanced stage when diagnosed. In addition, ovarian cancers often become chemoresistant and …