Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"EGL-20"”.
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New roles for Hox and Wnt in Cell Migration
… posteriorly. In QL, detection of extracellular EGL-20/Wnt results in trasncription of mab-5/Antennapedia/Hox through canonical Wnt signalling. MAB-5 is a posterior migration determinant of the QL lineage, and expression of mab-5 is necessary and sufficient for posterior migration. lin-39/Sex …
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Regulation of Neuronal Polarity by Wnt Signaling
… and PLM in C. elegans (Hilliard and Bargmann, 2006; Prasad and Clark, 2006). With the exception of one wnt/fz pair (lin-44/lin-17) the specific interactions between Wnt ligands and cell surface receptors in this process are unknown. A genetic screen was undertaken to identify genes that …
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Regulatory Architecture of Non-Apoptotic Cell Death Program in C. Elegans
… that two opposing spatial cues, the Wnt ligands EGL-20 and LIN-44, cooperate with LIN-29 to control linker cell death initiation. I showed that the Abdominal- B-like Hox transcription factor NOB-1 likely acts upstream of these two Wnt pathways, and that the Tailless/Tlx nuclear hormone receptor …
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New Insights into the Regulatory Network Controlling Neuroblast Migration in C. elegans
… Wnt signaling. Following the initial migrations EGL-20/Wnt is secreted and activates the canonical Wnt pathway in QL leading to the expression of MAB-5/Hox, which is necessary to drive QL migration towards the posterior. QR does not activate the canonical Wnt pathway, resulting in no MAB-5/Hox …