Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 7 of 7 for “"EGFR-Mutation"”.
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Epidemiology of non-squamous non-small cell lung cancer in New Zealand: A focus on EGFR gene mutation
… that target Epidermal Growth Factor Receptor (EGFR) significantly improves disease outcomes for non-squamous Non-Small Cell Lung Cancer (NSCLC) patients with EGFR mutation. A better understanding is needed of the epidemiology of lung cancer in relation to EGFR mutation and strategies to …
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Innovative Methods for Outcome-Based Pricing of Treatments from the US Payer Perspective (The Six Delta Platform)
… (NSCLC) with epidermal growth factor receptor (EGFR) mutation.
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Implementation and Cost Analysis of Performing Molecular Assays using FFPE Tissue Blocks in the Clinical Laboratory at VA Palo Alto Health Care System
… Care System, FFPE samples for BRAF, KRAS and EGFR mutation detection assays are usually sent out to reference laboratories. However, with the increasing demand and cost of these tests, it would be more cost effective to bring these assays to be performed in-house. The activities for this …
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Epidermal growth factor and Transforming growth factor α motogenic activities are mediated by Epidermal growth factor receptor : Identification of signalling pathways involved in head and neck cancer
… alteration of Epidermal Growth Factor Receptor (EGFR) plays a major role in the development of Head and Neck cancer. However, the only FDA approved EGFR target for this neoplasm is the drug Cetuximab. Cetuximab can only be used where there is an over-expression of EGFR. Cetuximab works by …
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Characterization of mTOR Inhibition and Autophagy Inhibition in Non-Small Cell Lung Cancer
… RTK activation such as ERBB2 amplification or EGFR mutation or amplification, while KRAS and/or LKB1 mutations were associated with resistance. RNAi knockdown of various components related to mTOR signaling and autophagy produce a heterogeneous growth effect response in NSCLCs cells, and …