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Showing 1 to 20 of 42 for “"EGCG"”.

  1. Development of a topical epigallocatechin gallate (EGCG) formulation

    Proniuk, StefanThe University of Arizona.2000

    Epigallocatechin gallate (EGCG) is a potent polyphenoclic antioxidant extracted from green tea. Due to its antimutagenic and antitumor activities it is a promising candidate for use in topical formulations for skin cancer prevention. The overall objective of this dissertation was to develop a …

    arizona-thes Repository record

  2. ORAL ADMINISTRATION OF EPIGALLOCATECHIN-3-GALLATE (EGCG) IS A POTENTIAL THERAPEUTIC FOR CISPLATIN-INDUCED HEARING LOSS

    Borse, Vikrant

    … green tea extract, epigallocatechin 3-gallate (EGCG), which possesses anti-oxidant, anti-inflammatory and anti-tumor properties. Oral administration of EGCG to male Wistar rats reduced cisplatin-induced hearing loss, assessed by auditory brainstem responses. These changes were associated with a …

    siu-theses Repository record

  3. EGCG and voluntary exercise : an examination of treatment effects using the TgCRND8 mouse model of Alzheimer's disease

    Walker, Jennifer M., 1985-University of Missouri--Columbia2013

    … male mice. Additionally, research has shown that EGCG, a botanical polyphenol, can reduce amyloid-beta levels, mitigate oxidative stress and reduce some of the cognitive impairments associated with Alzheimer's disease in the Tg2576 murine model; however, oral administration of EGCG had not been …

    missouri Repository record

  4. Modified Green Tea Polyphenol, Palmitoyl-EGCG and Black Tea Theaflavins: Promising Natural Herpes Simplex Virus 1 and 2 Agents

    de Oliveira, Aline Moraes2021

    … Green tea’s polyphenol epigallocatechin gallate (EGCG), and its modification palmitoyl-EGCG (p-EGCG), along with black tea theaflavins TF1, TF2, TF3 have been used to study their antiviral effect against HSV type 1 (HSV-1) and HSV type 2 (HSV-2). These compounds with concentrations of 0, 6.25, …

    shu-thes Repository record

  5. The effects of green tea, green rooibos and their major flavonoids (EGCG and aspalathin) on testicular cell health in vitro

    Booysen, Robin AlvinUniversity of the Western Cape2021

    … the flavonoids: epigallocatechin gallate (EGCG, from green tea) and aspalathin (from green rooibos), are held as primarily responsible for their health benefits. These flavonoids are known antioxidants that can interact with proteins, carbohydrates and fats, making them bioactive compounds …

    western-cape Repository record

  6. Regulation of Tumor Necrosis Factor-alpha Signaling in Rheumatoid Arthritis Synovial Fibroblasts by Green Tea Polyphenol Epigallocatechin-3-gallate

    Riegsecker, SharayahUniversity of Toledo Health Science Campus2013

    … and destruction. Epigallocatechin-3-gallate (EGCG) is a polyphenol found in green tea that has been shown to have an anti-inflammatory effect in RA. Previous studies suggest that EGCG blocks IL-1β signaling pathways to inhibit angiogenesis and tissue destruction in RA. However, little research …

    ohiolink Repository record

  7. Protective Mechanism of Epigallocatechin-3-gallate against Helicobacter pylori- induced Gastric Epithelial Cytotoxicity via Blockage of TLR-4 Signaling

    이, 기명2011

    … of apoptosis. (-)-Epigallocatechin-3-gallate (EGCG), one of green tea catechins, is known to suppress H. pylori-induced gastritis through its antioxidative and anti-bacterial actions. In this study, we evaluated protective mechanism of EGCG against H. pylori-induced cytotoxicity in gastric …

    ajou Repository record

  8. Wirkung von Teecatechin Epigallocatechingallat auf den Energiestoffwechsel der Maus

    Friedrich, MaikaUniversität Potsdam

    … insbesondere dem Epigallocatechin-3-gallat (EGCG), werden zahlreiche positive Effekte zugesprochen (z. B. antioxidativ, antikanzerogen, antiinflammatorisch, Blutdruck und Cholesterinspiegel senkend). Die Mechanismen, die zu einer Reduktion der in Tierversuchen beschriebenen Körper- und …

    potsdam-diss Repository record

  9. Novel nutritional interventions in the manipulation of energy expenditure and blood glucose regulation in humans

    Rajashekar, V.University of Westminster2009

    … agents, L-Histidine and Epigallocatechingallate (EGCG). Supplementation of both LHistidine and pure EGCG in animal models has previously shown effects on components of energy balance and blood glucose regulation. Studies of their supplementation among humans are none (in case of L-Histidine) or …

    westminster Repository record

  10. Epigallocatechin Gallate in the Regulation of Insulin Secretion

    Yuskavage, Julia KathrynVirginia Tech2008

    … long-term effects of epigallocatechin gallate (EGCG) on insulin secretion and synthesis from clonal beta-cells (INS1E cells), rat islets, and human islets, using 0.1, 1, or 5 µM. We determined if EGCG decreased blood glucose in healthy rats acutely, using 50 or 150 mg/kg body weight (BW), and …

    vt Repository record

  11. RegulationofGap Junction Protein,Connexins in Immortalized Human Keratinocytes Cells(HaCaTcells)

    김, 병철2011

    … epicatechin (EC) and epigallocatechin gallate(EGCG) were used for this study. These substances were first applied on the HaCaT cell line according to their concentration. After they were cultured for 24 hours, the cytotoxicity was analyzed by quantitatively assessing the degree of cell growth, …

    ajou Repository record

  12. Effect of Epigallocatechin-3-gallate on a pattern separation task and hippocampal neurogenesis in a mouse model of Down syndrome

    Stringer, Megan Elizabeth2015

    … osteoclastogenesis. Epigallocatechin-3-gallate (EGCG), the main polyphenol in green tea, inhibits Dyrk1a activity. We have shown that a three-week EGCG treatment (~10mg/kg/day) during adolescence normalizes skeletal abnormalities in Ts65Dn mice, yet the same dose did not rescue deficits in the …

    iupui Repository record

  13. Epigallocatechin-3-gallate and tolfenamic acid induces apoptosis and growth inhibition in head and neck cancer : Involvement of NSAID activated gene-1

    강, 성운2013

    … and anti-oxidants.Epigallocatechin-3-gallate (EGCG), a major polyphenolic constituent of green tea, possesses remarkable chemopreventive and therapeutic potential against various types of cancer, including HNSCC. In addition to, NSAIDs have been clinically used as chemopreventive agents for …

    ajou Repository record

  14. Untersuchung zur kardioprotektiven Wirkung von (-) -Epigallocatechin-3-Gallat und pulsatiler Perfusion bei extrakorporaler Zirkulation mittels Herz Lungenmaschine im Ferkelmodell

    Mewes, MarieUniversität Leipzig

    … inwiefern diese durch pulsatile Perfusion oder EGCG-Gabe beeinflussbar sind. Zu diesem Zweck wurden 5 Versuchsgruppen mit jeweils 6- 9 Ferkeln der Rasse Angler-Sattelschwein im Alter von ca. 4 Wochen und einem Gewicht zwischen 8-15 kg gebildet: „Kontrollgruppe“, „Kontrollgruppe + EGCG“, …

    qucosa-diss

  15. Effects of water chemistry and panning on flavor volatiles and catechins in teas (Camellia sinensis)

    Sheibani, ErshadVirginia Tech2014

    … on extraction of epigallocatechine gallate (EGCG) and caffeine in green tea and oolong tea aqueous infusions. The extraction of EGCG and caffeine were lower when green tea was brewed in hard water compared to distilled water. Brewing green tea and Oolong tea in tap water resulted in higher …

    vt Repository record

  16. Development and Evaluation of a Niosome Carrier for Topical Use of Antioxidant

    Li, DanhuiResearchSpace@Auckland2014

    … (C) and (-)-epigallocatechin gallate (EGCG). Methods: An HPLC method was developed and validated for the determination of the compounds; preformulation studies were performed to study the physicochemical properties of the two compounds, such as partition coefficient, aqueous solubility …

    auckland-ms Repository record

  17. Molecular Basis and Modification of a Neural Crest Deficit in a Down Syndrome Mouse Model

    Deitz, Samantha L.2013

    … vitro with the addition of the Dyrk1a inhibitor, EGCG, a green tea polyphenol. We also confirmed that harmine, a more highly studied and specific Dyrk1a inhibitor, is capable of similar effects on proliferation of PA1 cell from E9.5 Ts65Dn embryos. Furthermore, when Ts65Dn pregnant mothers were …

    iupui Repository record

  18. Role of salivary films in assessing astringent compounds

    Gibbins, HannahKing's College London2013

    … if any, of PRPs. <br/>Epigallocatechin gallate (EGCG), a polyphenol containing a galloyl ring, interacts with MUC5B to a much lower extent than with PRPs. However, this interaction is enough to alter and enhance the binding of MUC5B and other salivary proteins shown to aggregate with polyphenols …

    kings Repository record

  19. Desenvolvimento de sucos mistos de frutas tropicais adicionados de luteína e epigalocatequina galato

    Faraoni, Aurélia SantosUniversidade Federal de Viçosa2009

    … de luteína e galato de epigalocatequina (EGCG). As proporções de cada polpa nas formulações foram definidas utilizando o delineamento de misturas simplex e estas formulações foram avaliadas por meio de análises físico-químicas e teste de aceitação. Os sucos formulados continham 35% de …

    brazil-ufv Repository record

  20. Účinek flavonoidů na vybrané biotransformační enzymy

    Procházková, EliškaUniverzita Karlova, Farmaceutická fakulta v Hradci Králové2015

    … (EGC), epigallokatechin-3-gallát (EGCG) a extrakt ze zeleného čaje - polyfenon 60 (P) ovlivňují životnost Caco-2 buněk a jaký mají účinek na aktivitu a expresi vybraných biotransformačních enzymů v těchto střevních buňkách - cytochromů P450 (CYP) isoforem 1A1, 1A2 a 3A, …

    charles-prague Repository record

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