Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"EB1"”.
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A escola a tempo inteiro : um estudo na EB1/PE de Machico da Região Autónoma da Madeira
Dissertação de Mestrado em Administração e Gestão Educacional apresentada à Universidade Aberta
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Identification of binding protein with kinesin18B
… homology(CH) domain at their N terminus and an EB1-like C-terminal motif at their C terminus : the functional importance of these domains has not been determined. Human EB1 family proteins, which include EB1, EBF3, and RP1, also associate with the tumor suppressor protein adenomatous polyposis …
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Identification of a novel role for Eb1 in the regulation of cell growth and G1-S phase progression in Drosophila / by Deborah Coates.
… characterise the G1-S phase role of Drosophila Eb1, dEb1, which was identified in a cyclin E genetic screen. A dominant modifier screen was undertaken to identify novel regulators of cyclin E, and cell cycle progression using a hypomorphic allele of cyclin E. One suppressor from this screen, …
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Characterization of GAR22 function in the regulation of red blood cell differentiation and cell migration
… differentiation of erythroid cells, including BTEB1 (basic transcription binding protein 1/ Krüppel-like factor 9) and the novel TR target gene GAR22 (growth arrest specific gene 2 on chromosome 22). The upregulation of GAR22 in terminally differentiated cells suggests that GAR22 might be …
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Replacement of Val3 In Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability, Complexes of Sperm Whale Myoglobin G65T With Phenol and Ethylene Glycol, and Structure of A Fragment of Human End-Binding Protein 1 (Eb1)
… OF A FRAGMENT OF HUMAN END-BINDING PROTEIN 1 (EB1).</p> <p>End-binding protein 1 (EB1) in the presence of other proteins regulates microtubule dynamics and chromosome separation. EB1 is composed of three domains; the N-terminal domain which binds to microtubules, an intermediate domain I and …
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Escolas a tempo inteiro na Região Autónoma da Madeira : estudo de caso
… Escolas Tempo Inteiro na RAM, nomeadamente na EB1/PE da Terça de Cima. Este trabalho é de carácter exploratório e representa um Estudo de Caso demarcado a uma parte da população alvo, docentes e encarregados de educação da EB1/PE da Terça de Cima no decorrer do ano lectivo 2006/2007. O plano …
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The identification of the Tao-1 kinase as a key regulator of microtubule dynamics
… Instead, Tao-1 appears to function together with EB1 in the regulation of microtubule plus end instability at the cell cortex. Two microtubule motor proteins, Khc and Khc-73, interact with Tao-1 in a yeast two hybrid screen, which hints at a possible role for the transport of Tao-1 along filaments …
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Regulation of Tubulin dynamics by the +Tip tracking protein Mal3
… Tip1 and Tea2. Mal3, the S. pombe homologue of EB1, is a highly conserved ubiquitous protein found to be at the centre of many MT related processes. Tip1 is a CLIP170 homologue and Tea2 a kinesin-like motor protein. The mechanism by which they target the growing end of MTs and stabilize them is …
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Functional Investigation of Trypanosoma brucei Microtubule Associated Proteins and Their Role in Cellular Morphogenesis.
… of canonical plus tip binding proteins (+TIPs) EB1 and XMAP215. Microtubule plus ends are organised in a highly reproducible pattern throughout the cell cycle. This organisation becomes disrupted when GB4L or TCP86 are depleted, showing that GB4L and TCP86 play critical yet distinct roles in …
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Marine algal virus communities along Southern African coasts
… Algoa Bay regions. A bloom terminating virus, EB1, is proposed for the Elands Bay bloom event. The Cerebos salt pans showed the greatest diversity of all samples analysed and novel halophilic algal viruses were identified in regions with the highest salinity.
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O clube de pais leitores do Agrupamento Vertical de Maria Lamas
… na Escola do Ensino Básico do Primeiro Ciclo – EB1 dos Castelos – Agrupamento Vertical de Maria Lamas, que tem como objectivo principal a promoção de hábitos de leitura nos alunos e o envolvimento na dinâmica das relações entre escola e família. Com esta intenção promoveu-se a cooperação entre …
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A NOVEL, RAS-INDEPENDENT ROLE FOR NF1 IN MICROTUBULE DYNAMICS AND DAMAGE REPAIR DICTATES SENSITIVITY TO T-DM1 IN HER2 POSITIVE BREAST CANCER.
… and redistribution of the tip-binding protein EB1. To date, only two MAPs, CLASP and SSNA1 have been found to recognize and modulate such MT damage. None of these proteins is commonly mutated in cancer, so the relevance of MT repair for tumorigenesis remains uncertain, despite the established …
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Novel cell-penetrating peptide-based vectors for siRNA delivery
… sequence (either AntpHD, Penetratin, HIV-Tat or EB1) fused to either the first dsRNA binding motif 1 (DRBM) or the tandem motifs (DRBMx2) from human PKR, which bind dsRNA with high avidity in a sequence independent manner. A panel of constructs were cloned, expressed in a bacterial cell system, …
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Microtubule Organisation in Normal and Colon Cancer Cells
… increase" in" cell" size,"and" redeployment"of" EB1" and" the" microtubuleNactin" crosslinking" protein" ACF7" along" the" microtubule" lattice.""These"effects"could"be"rescued"by"transfection"with"mCherryNEB2.""Analysis" revealed" EB2" depleted" cells" possessed" less" dynamic" microtubules." " …
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HDAC6 activity is required for efficient polarization and intracellular transport of organelles in directionally migrating cells
… and p150Glued. Paradoxically, localization of EB1, a MT plus-end binding protein involved in an mDia-mediated MT stabilization pathway was not affected. The localization of CLIP170, another MT plus-end binding factor related to p150Glued and known to be important for the recruitment of CLASPs …