Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 12 of 12 for “"EAAT3"”.
-
Design, Synthesis and Biological Evaluation of a Family of Excitatory Amino Acid Transporter 3 (EAAT3) Preferring Inhibitors
… of the biological activity of a family of EAAT3 preferring inhibitors, L-β-benzyl aspartate (L-β-BA) and L-β-BA derivatives. L-β-BA and derivatives were initially synthesized in an approximate 2:1 ratio of diasteromers (threo:erythro), using base promoted enolate …
-
Design, Synthesis and Biological Evaluation of a Family of Excitatory Amino Acid Transporter 3 (EAAT3) Preferring Inhibitors
… of the biological activity of a family of EAAT3 preferring inhibitors, L-β-benzyl aspartate (L-β-BA) and L-β-BA derivatives. L-β-BA and derivatives were initially synthesized in an approximate 2:1 ratio of diasteromers (threo:erythro), using base promoted enolate …
-
Developmental Gene Expression in the Small Intestine of Chickens from Lines Divergently Selected for High or Low Juvenile Body Weight
… PepT1, the glutamate/aspartate transporter EAAT3, the sodium-dependent glucose transporter SGLT1, and the fructose transporter GLUT5 in the small intestine of chickens from lines divergently selected for high (HH) or low (LL) eight-week body weight and their reciprocal crosses, (HL and LH). …
-
Dietary and Developmental Regulation of Nutrient Transporter Gene Expression in the Small Intestine of Two Lines of Broilers
… CAT1, CAT2, LAT1, y+LAT1, y+LAT2, BoAT and EAAT3), four sugar transporters (SGLT1, SGLT5, GLUT5, and GLUT2), and a digestive enzyme, APN. For PepT1, Line B had greater quantities of mRNA compared with Line A (P = 0.001), suggesting a greater capacity for absorption of AA as peptides. Levels …
-
Pharmacological Modeling and Regulation of Excitatory Amino Acid Transporters (EAATs)
… recently characterized preferential inhibitor of EAAT3, to identify possible differences between EAAT2 and EAAT3.<p> Functional studies on the EAATs also led to the identification of a putative modulatory mechanism that is specific for EAAT1. Thus, a series of sulfated neuroactive steroids, …
-
Pharmacological Modeling and Regulation of Excitatory Amino Acid Transporters (EAATs)
… recently characterized preferential inhibitor of EAAT3, to identify possible differences between EAAT2 and EAAT3.<p> Functional studies on the EAATs also led to the identification of a putative modulatory mechanism that is specific for EAAT1. Thus, a series of sulfated neuroactive steroids, …
-
Regulatory Balance Between the Peptide Trasporter, Pept1, and Amino Acid Transporter Gene Expression in the Enterocyte
… CAT2, LAT1, y+LAT1, and y+LAT2, but not PepT1, EAAT3, Bo,+AT, or LAT2, making this model similar to the basolateral membrane of enterocytes. Growing MSIE cells at high temperatures did not affect the nutrient transporter gene expression profile of these cells. Thus, the human colon carcinoma …
-
Small Intestinal Transporters in Two Species of Galliformes: Male and Female Turkey (Meleagris gallopavo) and Chicken (Gallus gallus)
… (PepT1), amino acid (ASCT1, bo,+AT, CAT1, EAAT3, LAT1, y+LAT2), and sugar transporter expression (GLUT2, GLUT5, SGLT1) in the small intestine of male and female turkeys. Small intestine samples were collected during embryonic development (E21, E24) and DOH. In a separate experiment during …
-
Expression of Digestive Enzymes and Nutrient Transporters in the Intestine of Eimeria-challenged Chickens
… Pept1, ASCT1, bo,+AT/rBAT, B0AT, CAT1/2, EAAT3, LAT1 and y+LAT1/2, sugar transporters: GLUT1, GLUT2, GLUT5 and SGLT1, mineral transporter: ZNT1 and an immune factor: LEAP2 in the duodenum, jejunum, ileum and ceca of Eimeria-challenged layers and broilers. Comparisons were made between E. …
-
Gene Expression of Nutrient Transporters and Digestive Enzymes in the Yolk Sac Membrane and Small Intestine of the Developing Embryonic Chick
… transporter PepT1, amino acid transporters EAAT3, CAT1, and B0AT, monosaccharide transporters SGLT1 and GLUT5, and digestive enzymes APN and SI. Expression of these genes was measured in YSM at embryonic day (e) 11, 13, 15, 17, 19, 20, and 21 and small intestine at e15, e17, e19, e20, and …
-
Effects of Incubation Temperature and Transportation Stress on Yolk Utilization, Small Intestine Development, and Post-Hatch Performance of High-Yield Broiler Chicks
… nutrient transporter (SGLT1, GLUT2, GLUT5, EAAT3, and PepT1) gene expression. The objective of the second study was to evaluate the effects of embryonic incubation, simulating a multi-stage incubation system, and post-hatch transportation temperatures on post-hatch performance, yolk free …
-
Expression der Glutamattransporter GLT1 und GLAST im Gyrus dentatus der Ratte nach Läsion der Regio entorhinalis
… oder EAAT1 (Storck et al., 1992), EAAC1 oder EAAT3 (Kanai & Hedinger, 1992), EAAT4 (Fairman et al., 1995) und EAAT5 (Arriza et al., 1997). GLT1, GLAST und EAAC1 werden im gesamten ZNS exprimiert (Kanai & Hedinger, 1992; Pines et al., 1992; Storck et al., 1992; Rothstein et al., 1994; Torp et …