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Showing 1 to 20 of 98 for “"E6"”.

  1. E6 inspired supersymmetric models

    Howl, RichardUniversity of Southampton2009

    … are inspired by supersymmetric models with an E6 gauge group. The models are non-minimal supersymmetric theories which keep the Higgs mass stable against the quantum corrections from higher energy physics, but do not contain the mu-problem or little hierarchy problem of the Minimal …

    soton Repository record

  2. Small Molecule Inhibitors of HPV16 E6

    Yuan, Chung-Hsiang

    … nearly all cases of cervical cancer. HPV 16 E6, one of two viral oncogenes, protects cells from apoptosis by binding to and accelerating the degradation of several apoptotic proteins, including caspase 8 and p53. We proposed that blocking the interactions between HPV E6 and its partners using …

    loma-linda Repository record

  3. Anti-tumor Mechanisms of HPV16 E6*

    Evans, Whitney S.

    … intensively on the activities and roles of E6 proteins from HR-HPVs during the process of cellular transformation, clearly implicating E6 as a major transforming agent. In contrast, the role of the smaller splice isoform, E6*, in the carcinogenic process has not yet been established. Based …

    loma-linda Repository record

  4. String inspired QCD and E6 models.

    Boyce, Michael M.Carleton University1996

    carleton Repository record

  5. HPV16 E6* Induces Oxidative Stress and DNA Damage

    Williams, Vonetta M.

    … The high-risk types encode two viral oncogenes, E6 and E7, which work together to initiate cell transformation. The approximately 50 amino acid product of the E6* transcript is expressed during the early stages of HPV infection. In this study, we found that expression of E6* increased the level …

    loma-linda Repository record

  6. Influence of Human Papillomavirus 16 E6 on TRAIL-Mediated Apoptosis

    Garnett, Theodore O.

    … this study, we examined the influence of HPV 16 E6 on TRAIL-induced FADD-dependent and -independent pathways in two cellular models: HCT116 colon carcinoma cells and U2OS osteosarcoma cells. We show that transfection of the HPV 16 E6 oncogene into HCT116 cells provides protection from …

    loma-linda Repository record

  7. THE ROLE OF E6 PROTEIN IN HUMAN PAPILLOMAVIRUS ASSOCIATED UPPER AIRWAY DISEASES

    Wang, Jia2021

    … a subset of head and neck cancers, respectively. E6 protein is considered one of the oncoproteins encoded by high-risk HPVs, due to its ability to degrade tumor suppressor p53, activate telomerase, avoid apoptosis and other functions that contribute to carcinogenesis. Most of the functions of …

    tdl Repository record

  8. THE ROLE OF E6 PROTEIN IN HUMAN PAPILLOMAVIRUS ASSOCIATED UPPER AIRWAY DISEASES

    Wang, JiaThe University of Texas Medical Branch at Galveston2021

    … a subset of head and neck cancers, respectively. E6 protein is considered one of the oncoproteins encoded by high-risk HPVs, due to its ability to degrade tumor suppressor p53, activate telomerase, avoid apoptosis and other functions that contribute to carcinogenesis. Most of the functions of …

    utmb Repository record

  9. Mechanism of Human Papillomavirus E6-Mediated Repression of P53-Target Gene *Transcription

    Thomas, Mary C.University of Illinois at Urbana-Champaign2015

    … a new paradigm for human papillomavirus (HPV) E6 oncoprotein-mediated repression of human p21 WAF1 cyclin-dependent kinase inhibitor gene transcription, independent of its well known role to promote the ubiquitination and degradation of p53. Using both high-risk and low-risk HPV E6 …

    uiuc Repository record

  10. The mechanisms of differentiation-dependent regulation of HPV-11 E6 promoter and enhancer.

    Zhao, Wei

    uab Repository record

  11. The role of human papillomavirus type 16 E6 and E7 oncoproteins in angiogenesis

    Toussaint-Smith, Esra2003

    This document only includes an excerpt of the corresponding thesis or dissertation. To request a digital scan of the full text, please contact the Ruth Lilly Medical Library's Interlibrary Loan Department (rlmlill@iu.edu).

    iupui Repository record

  12. The role of human papillomavirus (HPV) E6 proteins as a risk factor for oesophageal cancer

    Ross-Innes, Caryn SarahDivision of Medical Biochemistry2007

    … HPV transforming gene has been shown to be E6. In this project, the effects of HPV11 E6, a low-risk type, and HPV18 E6, a high-risk type, were investigated by transfecting HPV-negative cell lines (EPC2-hTERT, MCF12A and Rat1) with HPV11 and HPV18 E6.

    cape-town Repository record

  13. Irreducible components of the restricted nilpotent commuting variety of G2, F4 and E6 in good characteristic

    Johnson, Heather, Levy, Paul, Towers, DavidLancaster University2015

    … in good characteristic p. We do the same for g = E6 with the exception of three nilpotent orbits. We use this information to determine the irreducible components of the restricted nilpotent commuting variety C1nil(g)= {(x,y) ∈ N1×N1 : [x,y] = 0} for g = G2 and F4. We do the same for g = E6 with …

    lancaster Repository record

  14. HPV E6 inhibits E6AP to regulate epithelial homeostasis by modulating keratinocyte differentiation commitment and YAP1 activation

    Yin, WenUniversity of Cambridge2023

    … common viral targets of low-risk and high-risk E6 proteins, E6AP and NHERF1, on the key components of epithelial homeostasis: cell density, proliferation, commitment to differentiation and basal layer delamination. Importantly, we demonstrate that deletion of E6AP in keratinocytes delayed the …

    cambridge Repository record

  15. Beteiligung der Gene E6 und E7 des Mastomys natalensis Papillomvirus an der Entstehung von Hauttumoren in transgenen Mäusen

    Helfrich, IrisUniversität Heidelberg

    … Arbeit untersucht die Beteiligung der E6- und E7-Onkoproteine des kutanen Mastomys natalensis Papillomvirus (MnPV) an der Entstehung von Hauttumoren in transgenen Mäusen. Durch den Einsatz MnPV-E6-transgener Mäuse in eine Mehrstufenkarzinogenese konnte gezeigt werden, daß das kutane …

    heid-diss Repository record

  16. Analysis of HPV 18 E6/E7 oncogenes expression in association with DNA amplification from integrated HPV segments in HeLa cells

    Sumerina, Alina2005

    tartu

  17. Efeito da concentração de nanopartículas de ZnO (ZnO-NP) na atividade antibacteriana e nas propriedades físicas e químicas de compósitos experimentais

    Souza, Natasha Lamêgo Brandão de2016

    … E1= 0%, E2= 0,5%, E3= 1%, E4= 2%, E5= 5% e E6= 10%. A análise do potencial antibacteriano foi avaliada através da atividade metabólica pela redução do MTT [3– (4, 5- dimetiltiazol- 2- yl)- 2, 5- brometo de difeniltetrazólio] e pela produção de ácido lático por biofilme de Streptococcus …

    brazil-uff Repository record

  18. NOVEL THERAPEUTIC STRATEGIES IN LUNG CANCERSTRONG BIOLOGICAL BIAS FOR ALK INTRON 19 BREAKPOINTS IN NON-SMALL LUNG CANCER

    LEONARDI, GIULIA COSTANZAUniversità degli studi di Catania2020

    … from the endogenous loci. EML4 exons 1-6 (E6) or exons 1-13 (E13) with different ALK exons: E6;A18, E6;A19, E6;A20 or E6;A21 and E13;A18, E13;A19, E13;A20, E13;A21. The fusions E6;A21 and E13;A21 contained an early stop codon not producing functional proteins. These EML4-ALK fusions were …

    catania Repository record

  19. Desarrollo de sistema lentiviral para la codificación de un short hairpin RNA que permite el silenciamiento dual de las oncoproteínas E6 y E7 de HPV16 en células de pulmón humano

    Parra Rivas, Bárbara AndreaUniversidad de Chile2013

    … de HPV16 está mediada por la sobreexpresión de E6 y E7 que inducen la pérdida de función de los genes supresores de tumor p53 y pRB respectivamente, siendo considerados el blanco ideal para el desarrollo de nuevas estrategias terapéuticas contra el cáncer. La producción de un intermediario de …

    chile Repository record

  20. Sustained Adrenergic Signaling Promotes Cervical Cancer Progression

    Sadaoui, Nouara C2014

    … through increased expression of HPV oncogenes, E6 and E7.</p> <p>Materials and Methods: ADRβ expression levels were examined in patient-derived cervical cancer samples. We used an orthotopic model of cervical cancer to investigate the effects of restraint stress on tumor growth and metastasis. …

    uthsc Repository record

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