Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 229 for “"E1"”.
-
Escherichia coli 2-oxoglutarate dehydrogenase multienzyme complex: e1 and e2 substrate specificty, e1 carboligase activity, and e2 interchain succinyl transfer
… (ThD P) dependent 2-oxogl utarate dehydrogenase (E1 o), a di hydrol i poylsucci nyl transferase (E2o), and a di hydrol i poyl dehydrogenase (E3). The first two components carry out the principal reactions for succinyl CoA formation while the third one reoxidizes dihydrolipoamide to lipoamide. This …
-
Resolvin E1 actions on polymorphonuclear neutrophils in diabetes
Diabetes and periodontal disease exhibit a bidirectional relationship centered on an enhanced inflammatory response manifested both locally and systemically. The observation that hyperglycemia by itself, in the absence of additional inflammatory signals, promotes a proinflammatory environment …
-
Novel Insights into Ubiquitin-like Protein E1-E2 Interactions
… occurs by a series of molecular handoffs down an E1‑E2‑E3 cascade. We are interested in understanding how E1‑E2 pairs interact and mediate UBL transfer. To this effect, we studied two E1‑E2 pairs: the Sumo pathway (Sumo utilizes a canonical E1 and E2) and the Atg8 pathway (Atg8 is a UBL involved …
-
Elucidation of antigenic epitopes on the rubella virus E1 glycoprotein
… HA epitope was mapped to amino acid residues E1214 to E12„ while two VN epitopes mapped to amino acid residues E1214 to E12, and E1219 to E1232. The potential use of the defined epitopes in the development of subunit vaccine is discussed.
-
Identification and Characterization of a New E1 That Activates Ubiquitin and FAT10
… modifications in eukaryotes. Three enzymes (E1, E2, and E3) are involved in conjugating ubiquitin to protein substrates. I identified a novel E1-like protein, E1-L2, which is homologous to the ubiquitin E1 and another E1 involved in the activation of the ubiquitin-like protein ISG-15 (E1-L1). …
-
Binding and Signaling Differences between Prostaglandin E1 and E2 Mediated by Prostaglandin E Subtype Receptors
Prostaglandin E1 (PGE1) and E2 (PGE2) are ligands for the prostaglandin E2 receptor (EP) family, which consists of four subtype receptors, designated as EP1, EP2, EP3 and EP4. Interestingly, PGE2 mediates inflammation whereas PGE1 acts as an anti-inflammatory factor. However, the molecular basis of …
-
The action of colocins E1 and K on proline transport in isolated membrane vesicles of E. coli.
Thesis: Ph. D., Massachusetts Institute of Technology, Department of Biology, 1971
-
Adaptation of Chikungunya virus to Aedes albopictus mosquitoes: The role of mutations in the E1 AND E2 glycoproteins
… with a strain of CHIKV with a mutation in the E1 glycoprotein (E1-A226V). Using viral infectious clones of Reunion and West African strains of CHIKV, into which either the E1-226 A or V residues were engineered, I demonstrated that the E1-A226V mutation was directly responsible for a …
-
Fast simulation of E1, B1 and Specific Absorption Rate for 7T MRI with the use of graphical processors
… This will allow us to estimate SAR, B1, and E1 fields quickly for instances where SAR estimation for parallel transmission imaging of individual subjects is necessary, or for optimizing coil designs based on these estimates. A fast FDTD computation would also significantly speed up iterative …
-
Effect of Prostaglandin E2 on Mechanical Stresses Applied by MC3T3-E1 Osteoblast-like Cells on a Soft Hydrogel Substrate
… These observations also suggest that the MC3T3-E1 cells communicate with one another mechanically by changes in substrate surface pattern by redistribution of the stresses applied but not by changes in the magnitude of these stresses. The Levenberg-Marquardt algorithm was found to perform at par …
-
Construction of bovine adenovirus type 3 E1 and E3, substitution plasmids and the sequencing analysis of DNA pol and pTP /
… this study, the objective was to rescue a BAV3 E1 or E3 recombinant vector carrying the kanamycin resistant gene, a dominant selectable marker with useful applications in studying vectored gene expression in mammalian cells. To accomplish the objective of this study, more information about BAV3 …
-
Utilizing Proteomic Techniques to Discover Host Protein Interactions with the E1 Glycoprotein of Venezuelan Equine Encephalitis Virus (VEEV) for Anti-Viral Discovery
… current market lacks available antibodies for E1 specific isolation. In response, a recombinant VEEV TC-83 was produced with a V5 tag at the C-terminal of the E1 sequence to enable VEEV E1 detection. Sequencing was used to verify V5 insertion in the plasmid and immunoprecipitation was used to …
-
The reliability and validity of the violence risk scale - experimental version 1
… Violence Risk Scale-Experimental Version 1 (VRS-E1, Wong & Gordon, 1996). The VRS-E1 was specifically designed to assess the risk of violence in offender populations. Using a sample of provincial and federal offenders (n=60), subjects were assessed with the VRS-E1 by two independent raters based …
-
An investigation of post-translational modification of human papillomavirus E4 and the role of modified E4 proteins during the virus life cycle
… etiological basis for cervical cancer. The HPV E1^E4 protein is proposed to be a major regulator of the HPV life cycle and the multiple and diverse activities associated with E1^E4 suggest that it is a multi-functional protein. This thesis has sought to address the hypothesis that …
-
Sorption, degradation and transport of estrogens and estrogen sulphates in agricultural soils
… Estrogens, namely 17β-estradiol (E2), estrone (E1), and estrogen sulphates, i.e. 17β-estradiol-3-sulphate (E2-3S) and estrone-3-sulphate (E1-3S) excreted by livestock constitute a potential source for estrogen contamination in the environment. A method was developed to separate and quantify the …
-
Proto-oncogene Regulation by Growth Factors in Bone Cells
… from these model systems. In contrast, MC3T3-E1 cells are a clonal mouse osteoblast-like cell line. Since MC3T3-E1 cells consist of a single population of calvarial cells, they make an ideal system in which to study the autocrine effects of bone growth factors.</p> <p>Based on this work, …
-
Development of poly(3-octylthiophene) thin films for regulating osteoblast growth
… poly(3-octylthiophene) (P3OT) to sustain MC3T3-E1 osteoblast attachment and growth. The central hypothesis was that specific P3OT film properties (i.e., thickness, film preparation conditions, and level of doping) are able to regulate osteoblast functions (i.e., attachment and proliferation). …
Page 1 of 12