Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 270 for “"E.coli"”.
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Lipoic acid assembly on 2-oxoacid dehydrogenases in E.coli
… aerobic metabolism is blocked. In Escherichia coli two pathways for the attachment of lipoic acid exist, a de novo biosynthetic pathway dependent on the activities of the LipB and LipA proteins and a lipoic acid scavenging pathway catalyzed by the LplA protein. LipB is responsible for …
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Investigation into the membrane interaction of E.coli Pencillin binding protein 4
… mass penicillin-binding proteins (PBPs) of E. coli play a regulatory role in the terminal stages of peptidoglycan biosynthesis. PBPs 4, 5 and 6 have been shown to possess DD-carboxypeptidase activity with PBP4 also having an endopeptidase activity. PBP5 and 6 are proposed to anchor to the …
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An Assessment of Potential False Positive E.coli Pyroprints in the CPLOP Database
… and <em>in silico </em>pyrosequencing of <em>E. coli </em>isolates housed in the Center for Applications in Biotechnology at California Polytechnic State University, San Luis Obispo that have matching pyroprints to show that it is<strong> </strong>possible to receive near identical pyroprints …
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A Computational Investigation of the Mechanism of CB1954 Reduction by E.coli Nitroreductase
… NTR (nitroreductase nfsB from Escherichia coli) and the prodrug CB1954 (5-[aziridin-1-yl]-2,4-dinitrobenzamide) have been found to be a good potential combination for virus-directed enzyme prodrug therapy (VDEPT). However, wild-type NTR has poor kinetics and binding with CB1954, and the …
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Regulation der Transkription: Struktur, Dynamik und Wechselwirkungen der carboxyterminalen Domäne von E.coli NusA
… durch Transkriptionsfaktoren reguliert. In E.coli wird die Entscheidung Elongation-versus-Termination an einem Terminator durch den allgemeinen Transkriptionsfaktor NusA beeinflußt. NusA assoziiert während der Elongation mit dem TEC und fördert sowohl Pausen während der Transkription als auch …
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Die Eigenschaften der Translationsinitiationsregion in E.coli: Effizienz verschiedener Signale aus dem Genom des Bakteriophagen T7
Im Rahmen dieser Dissertation wurden verschiedene Signalelemente, welche die Effizienz prokaryotischer Translationsinitiationsregionen (TIR) bestimmen, untersucht. Die TIR stark exprimierter Gene aus dem Genom des Bakteriophagen T7 weisen alle kurze Shine-Dalgarno (SD) Sequenzen (SD) sowie …
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Der Membranteil von H+-ATPasen : Struktur des CF0 aus Spinatchloroplasten, Funktion des EF0 aus E.coli
… zur Funktion des Membranteils EF0 aus E.coli hatten zum Ziel, das Zusammenwirken dreier konservierter Aminosäuren zu untersuchen. Es wird vermutet, dass Protonen durch die Membran entlang einiger für die Funktion essentieller Reste weitergereicht werden. In E.coli sind das u.a. R210 und …
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Overexpression of Human Aryl Hydrocarbon Receptor in <i> E.coli</i> Using Two Different Solubility Enhancing Tags
… on the expression of various AhR constructs in E.coli using recombinant DNA technology. As AhR forms inclusion bodies due to its poor solubility in the cytoplasm of the host bacteria, it is tagged as a “difficult to express” protein. Therefore, it is challenging to generate functional recombinant …
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Evaluation of Annotation Performances between Automated and Curated Databases of <i>E.COLI</i> Using the Correlation Coefficient
This project compared the performance of the correlation coefficient to show similarities in annotations between a predictive automated bacterial annotation database and the curated EcoCyc database. EcoCyc is a conservative multidimensional annotation system that is exclusively based on …
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The association between acute childhood diarrhoea and diarrhoeagenic E.coli present in contaminated soil in informal settlements in Durban
Submitted in fulfillment of the requirements of the degree of Master of Health Sciences in Environmental Health, Durban University of Technology, Durban, South Africa, 2016.
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Soluble and Functional Overexpression of the Ligand Binding Domain of Mouse Aryl Hydrocarbon Receptor in <i>E.Coli</i>
<p>The aryl hydrocarbon receptor (AhR) is a cytosolic ligand-activated transcription factor whose toxicity and carcinogenesis is mediated through various polyaromatic hydrocarbons and other environmental pollutants. The role of AhR in carcinogenesis is an area of concern due its altered levels in …
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Investigação de parâmetros bioquímicos em dois modelos animais de depressão induzidos por desamparo aprendido e administração do lipopolissacarideo de E.Coli
… and administration of lipopolyssaccharide from E.Coli (LPS). Learned helplessness protocol used in this work resulted in 70 % of helpless mice, assessed by the inability to escape from electroshocks given 24 h or 48 h after the helpless-induction session. The other 30 % of mice were considered …
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Investigation of the effects of antifolates on Escherichia coli 1810.
… test organisms were the sensitive Escherichia coli NCTC K-12 (E.coli K-12) and Escherichia coli 1810 (E.coli 1810) which was highly resistant to TMP. The checkerboard determinations indicated synergism with SD:TMP combinations against both E.coli strains. Viable counts also indicated that SD …
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Comparative enzymology of wheat germ aspartate transcarbamoylase and related studies
… have been elucidated and compared to the E.coli enzyme. Three types of essential amino acid residues have been demonstrated by chemical modification reagents. Essential arginine and lysine residues were studied by reaction with phenylglyoxal and pyridoxal 5'-phosphate respectively. In each …
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Use of Gamma Irradiation as an Intervention Treatment to Inactivate Escherichia coli O157:H7 in Freshly Extracted Apple Juice
<p><em>Escherichia coli </em>O157:H7 can contaminate dropped apples used for juicing via contact with manure or fecally tainted irrigation water and attach to the flesh of the apple through bruises and wounds where surface sanitizers are not effective. The goal of this project was to determine the …
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Characterization of a secreted escherichia coli 086a:K61 protease that inactivates human coagulation FV
Background: Escherichia coli (E.coli) O86a:K61 belongs to the Enteropathogenic E. coli (EPEC) group of pathogens. Acute gastroenteritis affects 2-4 billion people annually and EPEC is associated with 10-40% of hospitalized diarrhea cases globally. Coagulation Factor (F) V circulates as an inactive …
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Prevalence of Salmonella species and Escherichia Coli O157:H7 in organically managed cattle and food safety status of selected meat products
… ground beef was frequently associated with E.coli O157:H7 outbreaks. Salmonella spp., and E.coli O157:H7 are frequently associated with ground beef. Fermented sausage products were found to be a low risk food as the manufacturing process includes several hurdles for microbial growth. In fact, …
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Evaluation of the effects of gold nanoparticles (AuNPs) on protein folding in Escherichia coli
… interactions, their effect on E.coli growth as well as the effect on the solubility of E.coli proteins. The in vitro effects on DNA and protein integrity was also determined. The bacteria work was done by exposing E.coli to AuNPs. Imaging was done through TEM and bacterial growth …
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Effect of Heavy Metals on Bacteria
… this study was to find out the growth rate of E.coli and M.roseus in the presence of 1mM and 10 uM concentrations of cadmium and lead. E.coli and M.roseus were used due to their ability to grow in a controlled environment and ease of usage. The growth rates of the bacteria and viable counts were …
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Antibiotikaresistenzen bei Bakterien tierischer Herkunft
… bei Indikatorbakterien wie Enterokokken und E.coli Bedeutung beigemessen. <br>Diese Arbeit wurde mit dem Ziel ausgeführt, Anhaltspunkte für die momentane Resistenzsituation bei Bakterien tierischer Herkunft in Deutschland zu erhalten. <br>Dies soll zum einen eine Basis für den Vergleich mit …
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