Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 11 of 11 for “"Dyssynchrony"”.
-
Mechanical Dyssynchrony in Heart Failure and Implications for Response and Guidance of Cardiac Resynchronisation Therapy
… response rates have focused on pre-implant dyssynchrony following assumption that electrical dyssynchrony translates into mechanical dyssynchrony. Other factors that influence outcome are presence of myocardial scar and LV lead position. Cardiac magnetic resonance (CMR) imaging can quantify …
-
New methods for quantifying the synchrony of contraction and relaxation in the heart
… electrocardiogram QRS duration as a measure of dyssynchrony. However, up to 30% of patients selected for CRT show no improvement. This poor response rate may in part be explained by the poor correlation between mechanical dyssynchrony and QRS duration. Thus, better methods to quantify mechanical …
-
The role of myocardial fibrosis and ventricular mechanical dyssynchrony in the pathogenesis and treatment of contractile myocardial dysfunction.
… focussed on myocardial fibrosis and ventricular dyssynchrony. Myocardial fibrosis describes the extracellular deposition of collagen in response to an injurious process. This collagen deposition plays an important role in left ventricular remodelling, and may perpetuate myocardial dysfunction. …
-
Parameters and algorithms to evaluate cardiac mechanics by conductance catheter
… the phenomenon known as ventricular mechanical dyssynchrony: its impact on cardiac function, the therapy for its treatment and the methods for its quantification. Specifically, we describe the conductance catheter and its use for the measurement of dyssynchrony. At the end of the Section 1, we …
-
Mechanisms by which cardiac resynchronisation therapy improves cardiac performance in heart failure
… in those patients with evidence of electrical dyssynchrony and a broad QRS duration, a significant haemodynamic benefit was derived from an enhancement in left ventricular contractility, presumably as a result of a reduction in left ventricular dyssynchrony. Patients with external constraint …
-
Responding to resynchronization : improving the impact of biventricular pacing in the management of chronic heart failure
… of action is believed to be the correction of dyssynchrony of myocardial contraction. This approach can reduce morbidity and mortality in a select group of heart failure patients. However, many questions remain unanswered concerning the selection of patients for CRT, how to assess response to …
-
The pathophysiology of heart failure with preserved ejection fraction
… inefficiency as well as systolic and diastolic dyssynchrony as measured by speckle tracking imaging (STI). And that the LV anterior wall appears to be the most delayed segment. We also demonstrated that HfpEF patients exhibited chronotropic incompetence during peak exercise testing and abnormal …
-
High Resolution Multi-parametric Diagnostics and Therapy of Atrial Fibrillation: Chasing Arrhythmia Vulnerabilities in the Spatial Domain
… After confirming the presence of epi-endo dyssynchrony in multiple animal models, we further investigated the anatomical structure to look for regional trends in transmural fiber orientation that could help explain the spectrum of observed patterns. Simultaneously, we designed and optimized …
-
Comparative Effectiveness of Analgesic Sedation as Primary Sedation in Medical ICU Patients vs. Conventional Sedation and Analgesia Regimens
… pain, agitation, myocardial ischemia, ventilator dyssynchrony, intravenous line removal, self-extubation, and post-discharge complications, including post-traumatic stress disorder (PTSD). In contrast, over-sedation has been associated with prolonged mechanical ventilation, development of …
-
Heart failure and associated structural and functional remodeling: assessment employing various magnetic resonance imaging methodologies.
Cardiovascular magnetic resonance imaging (MRI), or cardiac MR, is currently considered the "gold" standard for noninvasively characterizing cardiac function and viability, having 3D capabilities and a high spatial and temporal resolution. More recently, the capabilities of MRI have been extended …