Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 2488 for “"Dysfunction"”.
-
dysfunction
dysfunction examines how we perceive normalcy and in turn, differentiate those who are abnormal through visual metaphors of the interior structures and features of the home. My thesis exhibition explores psychological disorders through installation, painting, drawing, sculpture and performance. The …
-
dysfunction
dysfunction examines how we perceive normalcy and in turn, differentiate those who are abnormal through visual metaphors of the interior structures and features of the home. My thesis exhibition explores psychological disorders through installation, painting, drawing, sculpture and performance. The …
-
Islet Dysfunction In Diabetes
… the mechanisms involved in pancreatic beta cell dysfunction in diabetes, specifically in elucidating the role of endoplasmic reticulum [ER] - mitochondria axis, executioner caspases and their target substrates; specifically nuclear lamins. </p> <p>Results obtained from our studies in pure beta …
-
The Legacy of Dysfunction
<p>N/A</p>
-
The Legacy of Dysfunction
<p>N/A</p>
-
Unraveling dual dysfunction in Friedreich’s ataxia: how mitochondrial dysfunction and microglial activation drive neurodegeneration
… When frataxin levels are depleted, mitochondrial dysfunction, increased oxidative stress, and impaired energy production are impacted which are central to understanding this disease. In order to determine if mitochondrial transplantation could be a viable treatment, we must first determine if we …
-
Immune Dysfunction in Cystic Fibrosis
Cystic Fibrosis (CF) is one of the most widespread life-shortening genetic diseases. CF is often diagnosed at birth; there is no cure, and many CF patients die from chronic lung disease at a young age. Patients with CF experience declining pulmonary function related to chronic airway infection, …
-
Nitrates and Left Ventricular Dysfunction
… patients with evidence of left ventricular (LV) dysfunction after acute myocardial infarction (AMI) already treated with standard heart failure (HF) therapy. Paper I. In a randomized, double-blind, placebo controlled trial, we evaluated the effects of a 60 mg dose of isosorbide-5-mononitrate …
-
ATHEROSCLEROSIS AND ENDOTHELIAL DYSFUNCTION IN THALASSEMIA
… in iron parameters, inflammation, or endothelial dysfunction related to ASCVD were found. Still, we discovered that sTfR, a marker of ineffective erythropoiesis, is greater in TNDT patients and in patients with atherosclerotic plaque, suggesting a possible role of ineffective erythropoiesis in …
-
Exercise Pressor Reflex Dysfunction in Hypertension
… in mediating both mechanoreflex and metaboreflex dysfunction in hypertension. To test this, we microdialyzed a NOS inhibitor, L-nitro-arginine methyl ester (L-NAME), and the NO precursor, L-arginine, into the NTS of normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive (SHR) rats to …
-
Calcium Channel Dysfunction in Huntington’s Disease
… extrinsic mechanisms involving early neuronal dysfunction in the cortex and striatum. One way in which cortical neuron function may be compromised is through alterations in the functional properties of the voltage gated ion channels underlying the action potential and synaptic transmission. …
-
Autonomic dysfunction in primary Sjögren's syndrome
… objective and subjective signs of autonomic dysfunction (AD) in patients with primary Sjögren’s syndrome (pSS) and to evaluate its clinical associations. In study I, 46 pSS patients and 56/80/238 autonomic nervous function test (ANT) controls participated. Objective signs of AD were evaluated …
-
β-cell dysfunction in Huntington's disease
… and account for neuronal as well as endocrine dysfunction. Hence, finding the mechanisms behind β-cell dysfunction in HD could identify potential therapeutic targets for the neuronal disease. Upon characterization of the R6/2 mouse model we found that mutant huntingtin renders β-cells …
-
Mitochondrial dysfunction in hereditary optic neuropathies
MITOCHONDRIAL DYSFUNCTION IN HEREDITARY OPTIC NEUROPATHIES Mitochondrial pathologies are a heterogeneous group of clinical manifestations characterized by oxidative phosphorylation impairment. At the beginning of their recognition mitochondrial pathologies were regarded as rare disorders but indeed …
-
Hanging-Associated Left Ventricular Systolic Dysfunction
… year-old) showed left ventricular (LV) systolic dysfunction (mean LVEF: 34 ± 16%). Global hypokinesia was presented in one patient. Apical ballooning with sparing of the basal segments was presented in 2 patients. Basal akinesia and apical hyperkinesia was presented in one patient. The other 4 …
-
Pelvic floor dysfunction in female triathletes
… is to describe the prevalence of pelvic floor dysfunction (PFD) in a female triathlete population. Methods: An anonymous on-line survey was administered from September 2015 to March 2016 to women who self-identified as triathletes. We used two validated questionnaires: the Pelvic Floor Distress …
-
Mtorc1 Signaling In Memory Formation and Dysfunction
… the role of mTORC1 in memory formation and dysfunction.</p> <p>It has been shown that in response to traumatic brain injury (TBI), mTORC1 activity is acutely increased, and treatment with rapamycin, a specific inhibitor of mTORC1, has been shown to improve outcome. On the other hand, chronic …
-
Cerebrovascular dysfunction : associations with midlife risk factors
… associated with an early marker of cognitive dysfunction, functional connectivity, and whether this relation was modified by physical fitness or physical activity status. We determined the moderating effect of physical fitness on the association between elevated plasma glucose and functional …
-
Improving differential diagnosis of vocal cord dysfunction
… in the literature to differentiate vocal cord dysfunction (VCD) from breathing difficulties of other etiologies accurately predict and identify patients who have VCD. The researchers were also interested in whether patients with VCD have a higher risk of misdiagnosis than patients with …
Page 1 of 125