Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 9 of 9 for “"Dynamic PET"”.
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Improved statistical quantitation of dynamic PET scans
Positron emission tomography (PET) scanning is an important diagnostic imaging technique used in the management of cancer patients and in medical research. It plays a key role in a variety of tasks related to diagnosis, therapy planning, prognosis and treatment monitoring by injecting a radiotracer …
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Statistical methods for mapping kinetics together with associated uncertainties in long field of view dynamic PET studies
Positron Emission Tomography (PET) is an essential diagnostic imaging technique in clinical care settings, as well as in medical research. It plays a crucial role in diagnosis, prognosis, treatment planning, and clinical decision-making. PET imaging, a well-established radio-tracer imaging …
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Motion Detection in Dynamic Cardiac Positron Emission Tomography Images
Dynamic PET is being increasingly utilized to quantify myocardial blood flow, leading to improved diagnostic and prognostic value for the management of coronary artery disease. MBF quantification assumes constant positioning of anatomical structures throughout image acquisition. This assumption is …
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Statistical analysis of 11CO2 contamination correction in 11C-acetate PET imaging studies
Positron Emission Tomography (PET) is a noninvasive imaging modality widely used in cancer management and medical research. It supports diagnosis, prognosis, treatment monitoring, and clinical decisions by tracking radiotracers labeled with positron-emitting isotopes. Tracer choice depends on the …
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Synthesis of fluorinated cannabinoid derivatives; Towards PET radiotracers for imaging the cannabinoid receptor
… such as positron emission tomography (PET), may be useful for understanding the complex role of the endocannabinoid system in animals and humans. Our major focus was to prepare novel fluorinated analogs of tetrahydrocannabinol (THC)-type, cannabidiol (CBD)-type, cannabicyclol …
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Statistical modeling strategies for estimation of the arterial input function in dynamic positron emission tomography data analysis
Kinetic modelling of dynamic PET data requires knowledge of tracer concentration in blood plasma, described by the arterial input function (AIF). Arterial blood sampling is the gold standard for AIF measurement, but is invasive and labour intensive. A number of methods have been proposed to …
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Improved quantification in small animal PET/MR
… imaging (MRI) and positron emission tomography (PET) provides excellent soft tissue contrast from MRI with exceptional sensitivity and specificity from PET. This thesis explores the use of sequentially acquired PET and MR images to improve the quantification of small animal PET data. The primary …
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Targeted Imaging Agents for Detecting Tumour Cell Death following Therapy
… in vitro and in vivo using biodistribution and dynamic PET imaging studies. Cell death detection was validated by cell death histology assays CC3 and TUNEL. For colorectal cancer, there was a positive correlation between [18F]FPenM-C2Am signal in tumours post treatment and the corresponding …
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Developing a selective sphingosine-1-phosphate-5 (s1p5) radiotracer to image oligodendrocytes using preclinical positron emission tomography (PET)
… to develop novel Positron Emission Tomography (PET) ligands to specifically bind to oligodendrocytes in the central nervous system in vivo. The ligands target the sphingosine-1-phosphate-5 (S1P5) receptor as a potential marker of oligodendrocyte function with PET. The ligands selected (TEFM180 …