Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Dynamic Membrane"”.
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Dynamic membrane interfaces shape biomolecular structure and function
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2024-09-16 without embargo terms
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Application of Genetically-Encoded Photoactivatable Crosslinkers to Map Ligand-Binding Sites on G Protein-Coupled Receptors
<p>G protein-coupled receptors (GPCRs) are dynamic membrane proteins that bind extracellular molecules to transduce biological signals. Although GPCRs represent the largest class of targets for therapeutic agents, ligand-binding sites have been precisely defined for only a small percentage of the …
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Characterization of a Novel Fis1 Interactor Required for Peripheral Distribution of the Mitochondrion of Toxoplasma Gondii
Toxoplasma’s singular mitochondrion is extremely dynamic and undergoes morphological changes throughout the parasite’s life cycle. While intracellular‚ the mitochondrion is maintained in a lasso shape that stretches around the parasite periphery and is in close proximity to the pellicle‚ suggesting …
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Rab8 Directs Tubulation and Furrow Ingression During Epithelial Formation in Drosophila Melanogaster
… in cell morphology is the formation of a plasma membrane furrow. The <em>Drosophila</em> embryo undergoes several cycles of rapid furrow ingression during early development, which culminates in the formation of an epithelial sheet. Previous studies have demonstrated the requirement for …
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Lipid rafts in protein sorting and yeast cell polarity
… are targeted via different pathways to distinct membrane compartments of the cell. The molecular principles that operate in cargo sorting at the TGN are still not very well understood. Especially, we know very little about the sorting of lipids. It was postulated that a sorting mechanism based on …
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Bioinformatics Discovery And Functional Characterization Of Lipid-Binding Lov Photoreceptors
… rapidly localize from cytoplasm to the plasma membrane upon blue-light illumination in a heterologous mammalian cell expression system. Dynamic membrane localization by BcRGS5 is mediated by a light-switchable high affinity electrostatic interaction with anionic phospholipids. The …
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Syncytiotrophoblast formation is influenced by genes involved in lipid biology
… fusion involving a lipid- signalling event and dynamic membrane rearrangement. Defects altering the structure and abundance of SynT cells in the labyrinth are enriched in embryonic lethal mouse mutants. From these findings, we are interested in understanding the regulation of lipid-related genes …
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Systems-Level Analysis of Rootstock–Scion Interactions in Apple Reveals Mechanisms of Cold Tolerance Under Field Frost Events
… MdHSFC1), ABA signaling, ROS detoxification, and membrane remodeling. Co-expression network analysis revealed frost-associated hub genes and regulatory modules. Carbohydrate profiling showed that B.9 maintained more stable soluble sugars—such as sucrose, glucose, and sorbitol—during …
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Analysis of SMAUG1 protein motifs and interacting partners - linking regulation of phase separation to human disease
… exert their functions through the formation of dynamic, membrane-less organelles (MLOs) via liquid–liquid phase separation (LLPS). Dysregulation of these MLOs or “biomolecular condensates” is increasingly linked to human disease, including cancer and neurological disorders. Human SMAUG1 (SAMD4A) …
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Electromechanical Characterization of the Static and Dynamic Response of Dielectric Elastomer Membranes
… a dielectric elastomer configured as a circular membrane clamped around its outer edge over a sealed chamber and inflated by a bias pressure is studied in order to characterize its static and dynamic electromechanical behavior. In both cases, the experiments were conducted with prestretched …
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Investigating spatial distribution and dynamics of membrane proteins in polymer-tethered lipid bilayer systems using single molecule-sensitive imaging techniques
Plasma membranes are complex supramolecular assemblies comprised of lipids and membrane proteins. Both types of membrane constituents are organized in highly dynamic patches with profound impact on membrane functionality, illustrating the functional importance of plasma membrane fluidity. Exemplary, …