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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 469 for “"Duplication"”.
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Genetic duplication in Salmonella typhimurium
A gene duplication occurs in Salmonella typhimurium which involves about 30% of the genome. The frequency of formation and loss of this duplication was determined in a Rec.A⁻ strain and a PolA⁻ strain and compared to that of a RecA⁺, PolA⁺ strain. The frequency of formation was found to be reduced …
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EPSPS gene duplication in Palmer amaranth: relative fitness, inheritance, and duplication mechanism of the glyphosate resistance trait
… to better understand the mechanism of EPSPS gene duplication through sequence assembly of the EPSPS amplicon and chromosomal localization of this duplicated region. The amplicon was extended out to a little over 110kb and was found to contain mostly repetitive sequence including long direct …
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Hox3 duplication and divergence in the Lepidoptera
… possible evolutionary significance of a set of duplications found in the Hox cluster of the Lepidoptera, called the Special Homeobox genes. An annotation of this duplicated cluster across a wide number of Lepidoptera was performed in order to assess patterns of duplication and loss across the …
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Homeobox gene and microRNA duplication in Chelicerata
… genes. The expansion of these toolkits via gene duplications is correlated with the evolution of multi-cellilarly and morphological complexity in metazoans. Small tandem duplications are a common source of additional genetic material in animals, while larger-scale events are relatively rarer and …
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Content Duplication Among Documents on Specific Subjects
An attempt was made to see how duplication of textual content among documents on the same specific medical subjects varied with time. Text analysis was performed on sets of documents that had been located with MEDLINE searches. Duplication of sentence segments between two documents was assumed to …
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Modeling Errors in Biometric Surveillance and De-duplication Systems
In biometrics-based surveillance and de-duplication applications, the system commonly determines if a given individual has been encountered before. In this dissertation, these applications are viewed as specific instances of a broader class of problems known as Anonymous Identification. Here, the …
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Gene duplication and the evolution of the higher diptera
<p>Gene duplication is an important source of evolutionary innovation. Using the publicly available genomic information, I studied lineage-specific gene duplications in <i>Drosophila melanogaster</i> (fruit fly), <i>Anopheles gambiae</i> (mosquito), <i>Tribolium castaneum</i> (red flour beetle), …
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Investigating the duplication and evolution of essential fertilization proteins
Duplication processes such as whole gene duplication and tandem domain expansion are important for the evolution and functional diversification of essential protein families. While whole gene duplications are well established sources of new genes and biological novelty, less attention has been paid …
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The Misexpression of Sonic Hedgehog Leads to Digit Duplication
… developing host tissue induces mirrorimage limb duplication. In addition to this, exposing embryos to exogenous Shh results in polydactyly. Polydactyly is a birth defect characterized by the presence of more than the normal number of fingers or toes. This defect with or without associated …
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Computational Tools for Metabolic Modeling and Gene Duplication Analysis
This thesis presents new computational methods to analyse both short and long-term effects of temperature increase on biological systems. First, we consider the problem of acclimation of an organism to increased temperatures on short timescales. We develop a novel method of network regression, …
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Generation of Directed Trees, 2-Trees and Paths Without Duplication
Made available in DSpace on 2014-12-08T22:23:43Z (GMT). No. of bitstreams: 1 6507149.pdf: 1357558 bytes, checksum: a5fe3032cd0e76c698fe719dac9667cb (MD5) Previous issue date: 1965
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Understanding How Whole Genome Duplication in Plants Impacts Herbivore-plant Interactions
… such prevalent change in plants is whole-genome duplication (WGD), or polyploidy, but we are still learning how WGD affects ecological interactions. In particular, studies of herbivory on polyploids have primarily focused on established polyploid plant populations. Although this approach has …
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Role of the Rcd4:Ana3 sub-complex in Drosophila centriole duplication
… of conserved proteins that govern the centriole duplication cycle. In an attempt to search for additional molecular components, two genome-wide RNA interference screens were conducted in cultured Drosophila cells (Dobbelaere et al., 2008; Goshima et al., 2007). While these studies significantly …
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Duplication is a prominent mechanism of recent gene birth in Caenorhabditis elegans
… using this dataset, I show that tandem gene duplication is a prominent gene birth mechanism, whereas horizontal gene transfer (HGT) played little or no role in the birth of recent C. elegans genes. Additionally, I show that G protein-coupled receptors (GPCRs) have high levels of …
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Investigating the role of gene duplication in the evolution and divergence of Arachnids
Gene duplication underlies the origin of novel genes with potential new functions that can contribute to organismal divergence. Relaxed selection on duplicates allows for the accumulation of mutations in coding and/or regulatory sequences of duplicated genes leading to subfunctionalization and/or …
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Using Duplication with Compare for On-line Error Detection in FPGA-based Designs
… in FPGA-based designs. This work introduces duplication with compare (DWC) as an automated on-line error detection technique that can be used as an alternative to readback with compare. This work also introduces a set of metrics that is used to quantify the effectiveness and coverage of this …
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Characterization of Germ-Line Events in an X-Chromosome Duplication in Drosophila Melanogaster
Made available in DSpace on 2014-12-12T00:51:24Z (GMT). No. of bitstreams: 1 7309973.pdf: 2983929 bytes, checksum: a8d8c6bf729fb93c6e8ea7be31bcdbfa (MD5) Previous issue date: 1972
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Evolution Via Gene Duplication and Alternative Splicing In The Eukaryotic Ski7 and Hbs1 Genes
<p>Gene duplication and alternative splicing are both recognized as important drivers of proteomic diversity and innovation during evolution, but the evolutionary changes over long periods of time or the interrelations of the two processes has not been extensively studied. Here I study these …
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Robust Content Identification and De-Duplication with Scalable Fisher Vector In video with Temporal Sampling
Robust content identification and de-duplication of video content in networks and caches have many important applications in content delivery networks. In this work, we propose a scalable hashing scheme based Fisher Vector aggregation of selected key point features, and a frame significance …
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Investigation of Cell-Type-Specific Effects and Synergistic Interactions Between Genes in Duplication 15q Syndrome
<p>Duplication 15q syndrome (Dup15q) is a genetic disorder caused by duplications of the 15q11.2-q13.1 region and is characterized by developmental delay, autism spectrum disorder, and treatment resistant epilepsy. Extra copies of the E3 ubiquitin ligase UBE3A and elevated levels of UBE3A …
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