Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 4 of 4 for “"Duocarmycins"”.
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Identification of determinants of sensitivity to duocarmycin analogues: A class of potent anti-cancer drugs
… Although the mechanism of action (MOA) of duocarmycins has been elucidated as DNA minor groove alkylation, not much is known about the factors involved in the intrinsic sensitivity of cancer cells to duocarmycins. This thesis aims to identify the determinants of sensitivity of duocarmycin …