Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"Ductal cell"”.
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The role of Arid1a and Tet1 in ductal cell-driven liver regeneration
Title: The role of Arid1a and Tet1 in ductal cell-driven regeneration Author: Mikel Alexander Mckie The liver has several robust and potent mechanisms of repair after damage despite slow homeostatic turnover. In cases of extreme toxic damage, where the hepatocyte compartment is severely compromised …
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The mesenchymal regulation of ductal-driven liver regeneration
Liver epithelial cells –hepatocytes and bile duct cells– intermingle with a microenvironment of endothelial cells, macrophages and mesenchymal cells to form the functional unit of the tissue. In chronic or severe liver injury, when hepatocyte proliferation is compromised, ductal cells become …
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Investigating the role of macrophage-epithelial cell interaction in salivary gland regeneration
… that CX3CR1+ macrophages home specifically to ductal cells following radiation injury, and that DNA damage is more severe upon the genetic depletion of macrophages compared to radiation alone. In addition, via in vivo analysis and a novel method for ex vivo live imaging, I show that macrophages …
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Developing a model to assess the contribution of cytokeratin 19-expressing cells during multipotent stromal cell-induced islet regeneration
… in human bone marrow-derived multipotent stromal cells (hMSC) generated conditioned media (CM) that promoted β-cell regeneration in streptozotocin-treated mice. Ductal-derived endocrine progenitors, which have been shown to generate β-cells following pancreatic injury, represent a candidate for …
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The Mechanism of Tumorigenesis In The Immortalized Human Pancreatic Cell Lines: Cell Culture Models of Human Pancreatic Cancer
… in the immortalized human pancreatic cell lines: cell culture models of human pancreatic cancer</strong></p> <p><strong> </strong></p> <p>Pancreatic ductal adenocarcinoma (PDAC) is the most lethal cancer in the world. The most common genetic lesions identified in PDAC include …