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Showing 1 to 3 of 3 for “"Drugs--Analysis."”.
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Investigating the role of commonly misused drugs in suspected unnatural and/or unexplained deaths in Cape Town in 2022
… accidental deaths, often require toxicological analysis to assist with determining the cause of death. In 2022, the Forensic Toxicology Unit within the Western Cape Forensic Pathology Service piloted a targeted drugs analysis at Salt River Mortuary in Cape Town. This permitted an assessment of …
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Molecular modeling of DNA with minor groove binding agents and intercalators
<p>The molecular modeling of several drugs in complexes with deoxyribonucleic acid (DNA) was undet1aken. Selected bis-lexitropsins, based upon NMR and modeling studies of bis-distamycin A, were modeled with an oligonucleotide d(CGAACA TGTTCG)2 using MidasPlus and AMBER 4.0. Intercalators ethidium, …
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Analysis of the Metabolism of Dextran-Methylprednisolone Succinate Using
… The efficiency of the assay was determined by analysis of samples with and without the extraction steps. All components were at least 80% extracted. Application of the assay to in vitro hydrolysis experiments included DexMPS incubation in rat blood and phosphate buffer, and in rat liver …