Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Drugs Design"”.
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Assay development for use in drug discovery against Bovine Trichomoniasis
<p>Bovine trichomoniasis is a venereal disease that affects cattle. The causative agent of this disease is <em>Tritrichomonas foetus</em>, a flagellated protozoan. There is no current FDA approved treatment for this disease. The purpose of this study was to develop new compound screening assays …
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Development of the single-molecule tracking and fluorescence lifetime techniques for biophysical measurements and biomedical applications
… can potentially facilitate the oligonucleotide drugs design or disease diagnosis. Additionally, the new lifetime imaging analysis method, flimGANE, is particularly useful in fundamental biological research and clinical applications with its advantages in speed and reliability.
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Design and synthesis of 3-[N-(cyclopropylmethyl) amino]-7-(methoxy or hydroxy)-2, 2-dimethyl-1-tetralone analogs as potential opioid receptor antagonists
<p>A series of 3-aminotetralins were synthesized as potential opioid antagonists. Each proposed target compound was based on a 3-(mono- or dialkylamino )-7 -(hydroxy or methoxy)-2, 2-dimethyl-1-tetralone parent structure. Three synthetic schemes were developed utilizing the common intermediate, …