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Showing 1 to 2 of 2 for “"Drugs -- Testing -- Statistical methods."”.
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Bayesian adaptive designs for non-inferiority and dose selection trials.
… can be used as the trial progresses. Bayesian methods offer a highly flexible means of using such information yielding inferences and decisions that are consistent with the laws of probability and consequently admit ease of interpretation. Bayesian adaptive sampling methods offer the potential …
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Sample size determination for Emax model, equivalence / non-inferiority test and drug combination in fixed dose trials.
… Informative priors are derived for component drugs and a non-informative prior is assumed for the drug mixture. Sample sizes are evaluated by posterior standard errors, average probability of more effectiveness and Bayesian power.