Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Drug trial,"”.
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The Effectiveness of Rating Scales and Semi-Structured Interview in Diagnosing Adult Attention Deficit Hyperactivity Disorder
… (18 to 60 years ofage) participating in a drug trial for adult ADHD. The CAADID interview results in a yes-no decision as to whether the patient meets <em>DSM-IV</em> criteria for the subtypes ADHD. A <em>t</em> -test was used to compare the CAADID-diagnosed and Not-Diagnosed subtypes with …
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A Comparative Study of the Pathology and Pathophysiology of Severe Malaria in a Non-Human Primate Model
With the rise in plasmodial drug resistance throughout the world, a dwindling arsenal of anti-malarials and a predilection for use of less than ideal murine models, the need for effective, applicable and established animal models through which to understand severe malarial disease and test …
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First-order statistical speckle models improve robustness and reproducibility of contrast-enhanced ultrasound perfusion estimates
… technique was tested in an antiangiogenic drug trial (bevacizumab) on tumor bearing mice (MDA-MB-231LN), and evaluated with gold-standard histology and contrast-enhanced X-ray computed tomography. The compound statistical model could more accurately discriminate anti-VEGF treated tumors …
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Anatomy of visual hallucinations and fluctuations of consciousness in Lewy body diseases
… with and without visual hallucinations. A drug trial of a cholinesterase inhibitor in this population was then performed to determine clinical effect and the impact of this drug on cerebral perfusion. These studies identified occipital hypoperfusion in Parkinson's disease patients with …
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Changes in cerebral glucose metabolism in patients with Parkinson’s disease with dementia after cholinesterase inhibitor therapy
… have been several reports describing how the drugs are benefiting the PDD patients in terms of clinical and neuropsychological scales. But there has never been a study on how the drug effect is represented on brain images. We performed serial 18FFDG PET studies in patients with PDD before and …
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Coping with HIV-seropositive status: a psychoneuroimmunological perspective
… homosexual men participating in an experimental drug trial were included in a psychoneuroimmunological investigation of the association between levels of short-term emotional distress, methods of coping, hopelessness, loneliness, joy, and CDS-cell counts, CD4-cell counts, and the cumulative rate …
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An Innovative Phase I Trial Design Allowing For The Identification of Multiple Potential Maximum to lerated Doses With Combination Therapy of Targeted Agents
… used both in medical practice and clinical trials. Korn and Simon listed three reasons for the utility of combinations: 1) biochemical synergism, 2) differential susceptibility of tumor cells to different agents, and 3) higher achievable dose intensity by exploiting non-overlapping …