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Showing 1 to 1 of 1 for “"Drug induced liveer injury"”.
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Understanding the transport mechanisms of BSEP to improve the prediction of DILI compounds
At present, Drug-Induced Liver Injury (DILI) is the most frequent cause of acute liver injury, with an incidence ranging from 0.023-1.5‰ in developed countries. DILI can be separated into two different types. Whereas intrinsic DILI concerns predictable dose-dependent hepatoxicity, idiosyncratic …