Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 12 of 12 for “"Drug detection"”.
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Validation of oral fluid as a matrix for drug detection
… in the courts. In recent years in workplace drug testing there has been a shift away from using traditional specimens (i.e urine) for drug testing and monitoring and a move to employing less invasive testing using oral fluid. Whilst it is now widely accepted that drugs can be detected in oral …
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Paper Spray - Mass Spectrometry: Investigation of Sampling Devices for Illicit Drug Detection and Quantification
… an alternate paper substrate to enhance drug detection on surfaces like asphalt, cloth, concrete, aluminum, and glass. Analysis occurs on a single spray ticket coated with pressure-sensitive adhesive (PSA), also known as Post-it notes to detect and quantify drug residues. A PS-MS method …
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Improvement and Development of Analytical Forensic Methods: Arson Investigation and Drug Detection in Fingerprints and Hair
… subsections of forensic science, arson and drug detection. The number of arson cases each year continues to grow and cause hundreds of thousands of dollars of damage. The study conducted in this research aimed to create a preliminary database of evaporated gasoline samples using the internal …
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Tailoring plasmonic substrates for SERS
… of the NPs introduced the possibility of drug detection or studies in drug delivery using such a system
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Towards Urine Sensing in Plasmonic Nanogaps
… of automating fluidic sensing platforms for drug detection in urine samples is realised. The developed system involves chromatographic separation to mitigate the effects of interfering compounds.
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Study of SERS for the detection of drugs of abuse
… Enhanced Raman Spectroscopy (SERS) for the detection of illicit drugs in oral fluid using metal enhancement mechanisms was undertaken. Initial work investigated ecstasy tablet composition using Raman to identify what drugs and excipients might be present in oral fluid samples obtained from …
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Substandard antimicrobial drugs: detection methods and their contributions to antibiotic resistance
… Substandard medicines vary from standard drugs in terms of dose, bioavailability, or the presence of impurities. Current methods to identify substandard and counterfeit antimicrobial drugs are either resource intensive or have poor specificity. This dissertation examined two issues related …
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Microfluidic Selection and Applications of Aptamers
… aptamer-coated microbeads and fluorescent detection. Secondly, a technology necessary for on-chip integration of SELEX is developed: a novel bead-based polymerase chain reaction (PCR) protocol which vastly simplifies procedures for the capture and resuspension of ssDNA in solution. This …
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The development of an electrochemical sensing device for controlled drugs.
… of substances to test when attending clandestine drug manufacture crime scenes. Whilst many techniques exist at their disposal - such as chemical colour test reagents and immunoassays - these methods are at best semi-quantitative and often subject to false positives. Electrochemical methods of …
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Determination of biomarkers for toxicity and antiretroviral adherence in hair in South African patients
… alcohol consumption over long time periods. Drugs of abuse are also detected in hair. Hair provides a longer window of drug detection compared to blood and urine. Recently, hair has also been studied as an alternative matrix for adherence monitoring and concentrations of antiretrovirals in …
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An evaluation of analytical procedures for detection of drug abuse with particular reference to opiates.
The results of a pre-employment drug screening programme for amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine and opiates involving some 1400 subjects by enzyme immunoassay, carried out by the author, are reported. The corresponding confirmatory tests by GC-MS on samples screening …
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SERS & efficacy assessment of anti-cancer drug-nanoparticle conjugates
… to treatement. Measuring the success of the drug at the intracellular level, for example: drug entry, accumulation and binding to its active site, can be difficult to observe directly when the drug is not labelled. Being able to determine the intracellular accumulation (concentration), …