Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Drug Resistance, Viral"”.
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Host-Based Mechanisms of Ribavirin Resistance: Implications In Treatment Response of Hepatatis C Virus Infection
… component of therapy with next-generation viral inhibitors, RBV’s mechanism is controversial. Most of RBV’s proposed mechanisms require RBV import into cells. Therefore, we examined whether host-based RBV resistance develops through reduced cellular uptake, analogous to chemotherapy …
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Construction of an HIV-1 subtype C ventor system for phenotypic drug resistance studies
… (RT) and protease (PR) gene as targets of antiviral therapy has led to the discovery of various major, minor and polymorphic mutations harbored thereof. There are mutations in HIV-1 subtype B strains that develop only under drug pressure leading to ARV drug resistance. These mutations have been …