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Showing 1 to 1 of 1 for “"Drosophila, neuroblast, Prefoldin, Pins, asymmetric division, dedifferentiation"”.
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ANALYZING THE FUNCTIONS OF PREFOLDIN COMPLEX IN NEUROBLAST HOMEOSTASIS OF DROSOPHILA MELANOGASTER
Prefoldin is a molecular chaperone that regulates tubulin function in mitosis. In this thesis, I show that Prefoldin depletion results in disruption of neuroblast polarity, leading to neuroblast overgrowth in Drosophila larval brains. Co-depletion of Prefoldin and Partner of Inscuteable (Pins) …