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Showing 1 to 1 of 1 for “"Drosophila, Nelf-A, healthspan, heat-shock proteins, heterochromatin, stress responses"”.
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STUDY OF EPIGENETIC REGULATORS AND SIGNATURES OF AGING
… transcription machineries may affect longevity. NELF-mediated pausing of RNA polymerase II (RNAPII) constitutes an important step in transcription regulation. I found that halving NELF-A level in heterozygous mutants or via neuronal-specific depletion of NELF-A improves locomotor activity, stress …