Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Drakenstein Child Health Study (DCHS)"”.
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Anaemia in early childhood pneumonia ? prevalence, predictors, and associated growth in the Drakenstein child health study (DCHS)
… and treatment. Methods: This cross-sectional sub-study analysed data from the Drakenstein Child Health Study (DCHS), a South African population-based birth cohort which enrolled pregnant women. Mother-child pairs were followed prospectively, and a subgroup of children had additional data collected …
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Growth and determinants at two years of age in a South African birth cohort
Aim: Early childhood is a critical period for optimal growth but there are limited data from low- and middle-income countries (LMICs) on the determinants of growth during this time. This study aimed to investigate growth and its determinants in children at 2 years of age in a South African birth …
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The house dust microbiota in the Drakenstein Child Health Study
… its' influence on human respiratory health. Aims: The aims of the studies described in this MSc dissertation were to: 1) evaluate the performance of ten commercial nucleic acid extraction kits on dust samples; 2) optimise dust removal from electrostatic dustfall collectors (EDC); 3) …
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Mental health and cognitive outcomes associated with early childhood violence exposure: a focus on children in low-middle income countries (LMICs)
… associations of violence exposure with mental health or cognitive functioning in this age group. This is important, given that children in LMICs experience a high burden of violence and therefore alongside policies to reduce violence exposure, understanding the impacts of violence can guide …
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The association of early childhood nutrition and growth with the intestinal microbiome and pneumonia
… infant feeding practices, and the microbiome in children with malnutrition and pneumonia in low and middle-income countries (LMIC) are scarce. This work aimed to investigate growth in early childhood, and associations of the microbiome with growth and pneumonia in an LMIC. Methods A prospective …
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Latent class modelling of respiratory outcomes in a South African birth cohort
… Early life is a key period determining long-term health, particularly in low-income and middle-income countries (LMICs) where negative exposures are common. This thesis focuses on two key respiratory outcomes: childhood wheezing and lung function. It examines (1) the underlying heterogeneity of …
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Ornithobacterium hominis isolates from a South African birth cohort
… hemisphere. Recent microbiome data from the Drakenstein Child Health Study (DCHS) has shown that O. hominis is present in South Africa; however, there is a lack of microbiological data regarding this species in Africa. Only a few strains have been isolated since its discovery, all of which …
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Perinatal suicidality: prevalence and correlates in a South African cohort
… – Data were collected from participants in the Drakenstein Child Health Study (DCHS) cohort during pregnancy and at 6 months post-partum (PP). SIB was measured using the MINI International Neuropsychiatric Interview (MINI). Self-report and clinician administered questionnaires assessed …
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Association of Faecalibacterium, Lachnospira, Veillonella, and Rothia with childhood wheezing
Wheezing symptoms among children, present major health and economic problems globally. A recent study conducted in Canada observed a reduction in stool bacterial genera Faecalibacterium, Lachnospira, Veillonella and Rothia (FLVR) in three-month old infants with atopy-wheeze symptoms. It is not …
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The association of maternal HIV status during pregnancy on longitudinal neuro-immune regulation, and neurodevelopment in HIV-exposed uninfected children
… access to antiretroviral therapy (ART), more children are now being born uninfected with HIV while still being exposed to the virus in utero. Exposure to HIV in utero may still negatively affect the developing brain of these children. However, the biological mechanisms involved in the …
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Prenatal alcohol exposure and the early neurodevelopmental outcomes of children in a South African birth cohort study
… alcohol exposure (PAE) has been a major public health problem both globally and in low- to-middle-income countries (LMICs) such as South Africa. Pregnant women and new mothers are particularly vulnerable; and PAE may be associated with adverse child neurodevelopmental outcomes. However, few …
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Investigating associations between maternal mental health on wheeze through two years of age in a South African birth cohort study
… one of the most common respiratory illnesses in children worldwide. Severe wheeze can result in significant morbidity, caregiver burden and increased health care costs. In addition, early childhood wheeze may be associated with reduced lung function, diminished airway responsiveness, increased …
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Indoor air pollution and environmental tobacco smoke exposure in a South African birth cohort study
… countries (LMIC) and a major reason for health care visits and hospitalisation. Environmental exposures to indoor air pollution (IAP) or tobacco smoke are important risk factors for childhood respiratory disease. Despite increased electrification, many communities in LMIC rely on …
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Genetic and epigenetic associations with child development and mental health in a South African birth cohort
Childhood developmental and mental disorders – including internalising and externalising symptoms – are prevalent in low- and middle-income countries (LMICs) such as South Africa. There is growing interest in the associations between polygenic risk scores (PRS), epigenetic age (EA) deviation, DNA …