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Showing 1 to 1 of 1 for “"Down syndrome, mouse models, EGCG, development, Dyrk1a"”.
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Molecular Basis and Modification of a Neural Crest Deficit in a Down Syndrome Mouse Model
Down syndrome (DS) is the result of trisomy of human chromosome 21 (Hsa 21) and occurs in approximately 1/700 live births. Mouse models of DS have been crucial in understanding the gene-phenotype relationships that underlie many DS anomalies. The Ts65Dn mouse model, trisomic for half of the Hsa 21 …