Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 32 for “"Double negative"”.
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Resonance and double negative behavior in metamaterials
… and is shown to exhibit frequency dependent double negative effective properties. We develop a rigorous method for calculating the frequency intervals where either double negative or double positive effective properties appear and show how these intervals imply the existence of propagating …
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Double Negative Metamaterials in Dielectric Waveguide Configurations
With the recent resurgence of interest in double negative (DNG) materials and the reported construction of a metamaterial with DNG characteristics, applications of these materials become feasible and examination of the behavior of systems and devices a potentially fruitful topic. The most promising …
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Development Of Thymic Natural Killer Cells From Double Negative 1 Thymocyte Precursors
… <italic> in vitro</italic> indicate that double negative: CD4<super>&minus</super>CD8<super>&minus</super>, DN) thymocytes can develop into cells with NK cell markers, but these cells have not been well characterized. Moreover, a subpopulation of NK cells which requires an intact thymus, …
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Allogeneic Double Negative T cell Therapy as a Novel Treatment for AML Patients
… Grail’ for allo-BMT patients. CD3+ CD4- CD8- double negative T cell (DNT) is an unconventional mature T cell subset found in periphery. In this thesis, I have developed a method to expand therapeutically-relevant numbers of clinical-grade DNTs obtained from healthy donors (HDs) and extensively …
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Tumor Suppressor APC and Musashi1: Double-Negative Feedback, Wnt Signaling and Colon Cancer
… the intestinal epithelium. I have identified a double-negative feedback loop between APC and a sequence specific RNA binding protein, Mushashi-1 (MSI1). I hypothesize that this feedback loop serves to maintain a critical balance and that disruption of this balance leads to loss of homeostasis …
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Theory, Simulation, Fabrication and Testing of Double Negative and Epsilon Near Zero Metamaterials for Microwave Applications
<p>Natural structures exhibiting simultaneous negative bulk permittivity and permeability have not yet been discovered. However, research interest over the past five years has grown with the proposition that artificial structures exhibiting these properties are realizable using specially-designed …
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Age-associated alterations in the immune system of normal and autoimmune-susceptible mice
… accumulate in the lymph nodes were studied. The double-negative T cells from the lymph nodes of old Ipr mice were found to express a cell surface marker, J11d, that is normally present only on immature T cells in the thymus. Furthermore, the number of double-negative J11d⁺ T cells also increased …
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Exact Solutions to Electromagnetic Scattering Problems with Multi-Layered Oblate Spheroidal Geometry
… a semi-oblate spheroidal cavity placed under a double-negative half-space. The cavity has two layers: one is made of double-positive material (DPS), the other is made of double-negative (DNG) metamaterial. The source of the incident field is an electric or magnetic dipole placed in the DNG …
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Immunophenotypic classification of canine malignant lymphoma in formalin-fixed, paraffin wax-embedded specimens using CD3 and CD79a cell markers
… 9.7% of the total number of lymphomas exhibited double negative staining. Only two categories, the immunoblastic and medium-sized macro nucleolated (MMC) category (Fournel-Fleury et al.). exhibited constant (8 cell) immunophenotype. All the other categories exhibited mixed immunophenotype. The …
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Exposing the pain and celebrating the triumphs of the black female spirit: an analysis of Alice Walker's In Love and Trouble
… the twentieth century involves dismantling the "double-negative stigma," a term used to describe the towering obstacles placed before the individual who is both Black and female. In addition, little nourishment has been given to those labeled powerless and unimportant, whereas our society has …
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Transmembrane glycoprotein gp41 of the Human Immunodeficiency Virus Type I : gene synthesis, recombinant expression and immunological characterization
… on CD1 as a “lipid like” peptide to CD4/CD8 double negative T-cell or NKT cells. Auto-immunity may be of some concern, because antibodies and other forms of immunity induced by the CD4/CD8 double negative T-cell population are often involved in auto-immunity. Many viruses have, as part of …
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Free-Space Measurements of Dielectrics and Three-Dimensional Periodic Metamaterials
… under test. The results show epsilon-negative, mu-negative and double-negative parameters within the measured frequency range. </p>
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Transcriptional Regulation of Muscle Contractility and Metabolism by a MicroRNA-Mediated Feed Forward Loop
… The MyomiRs influence myofiber phenotype by negatively regulating the transcription factor Sox6, in addition to several other functionally related transcriptional repressors. Subsequent studies identified Sox6 as a fast myofiber enriched repressor of slow muscle gene expression. Mice lacking …
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Microrna-200 Regulates Ecm-Dependent Β1-Integrin/Fak Signaling and Cancer Cell Invasion
… transition, partially through its double-negative feedback loop with the transcriptional repressor Zeb1, yet the mechanisms on how miR-200 controls the invasive phenotype are not fully understood. Recent studies have shown that the miR-200/Zeb1 axis regulates cell-cell and …
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Innovative Multivariate Meta-Analyses Methods For Diagnostic Tests And Multiple Treatments
… evaluate sensitivities by incorporating the double-negative results. We apply the method to evaluate the diagnosis accuracy of SARS-CoV-2 infection using saliva sampling or nasopharyngeal swabs. Through simulations, our method shows improved performance over the pragmatic reference standard …
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The immunomodulatory properties of AZT used in the treatment of AIDS
… from a significant decrease in the number of double-positive (CD4⁺CD8⁺) cells and an increase in the number of double-negative (CD4⁻CD8⁻) cells. Interestingly, after the i.p. administration of interleukin-2 (IL-2) simultaneously with AZT, the total cellularity of the thymus was completely …
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Crossing the Line: Censorship, Borders, and the Queer Poetics of Disclosure in English-Canadian Writing, 1967-2000
… Daphne Marlatt and Betsy Warland’s long-poem Double Negative (1988), an experimental narrative of their Australian travels. Marlatt and Warland’s erotic, language-mediated poetics evade both censure and the individualism of free speech discourse by questioning the limits of lyric expression. …
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Effect of homozygous lpr and gld mutations on the immune functions and induction of autoimmunity
… by the accumulation of unique CD4⁻CD8⁻ (double-negative, DN) T cells. Because of these poor functions in vitro, the nature and significance of DN T cells in the autoimmune disease process is not clear. In the current study we found that <i>lpr</i> DN T cells could mediate spontaneous …
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Inhibition of Heat Shock Protein 90 Reduces Inflammatory Signal Transduction in Murine J774 Macrophage Cells and Lessens Disease in Autoimmune MRL/lpr Mice: What in vitro, in vivo, and in silico Models Reveal
… of splenocytes showed that 17-DMAG decreased double negative T (DNT) cells. Renal expression of HSP90 was also measured and found to be increased in MRL/lpr mice that did not receive 17-DMAG. The mechanistic interactions between HSP90 and the pro-inflammatory nuclear factor-κB (NF-κB) pathway …
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