Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 1 of 1 for “"Dose-to-duration"”.
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Identification of the molecular pathways that mediate cytokine induced immunopathology of the gut epithelium
… are still not clear. The main aim of my PhD was to identify the mechanisms which are required for the killing of human intestinal epithelial cells (Chapter-I) by this cytokine combination. A human kinome RNAi screen and a drug repurposing screen identified the Janus kinases (JAKs) JAK1 and JAK2 …